Metabolism — Flashcards

what are the followings in relation to Phenylalanine metabolism? -Dihydrobiopterin reductase -Dopamine B-hydroxylase -Dopamine decarboxylase -Phenylalanine hydroxylase -Phenylethanolamine N-methyltransferase -Tyrosinase

In what disease the followings are associated with? -Delta-Aminolevulinate dehydratase -Delta- Aminolevulinate synthase -Bilirubin glucuronyl transferase -Porphobilinogen deaminase -Uroporphyrinogen decarboxylase

11 y/o girl is evaluated for blurry vision. - Physical Exam: bilateral lens opacities -Urine is positive for reducing substances. -Deficient activity of which enzyme is the most likely cause of this patient's eye condition?

In what reaction Xylulose will be found?

What are the following amino acids? -Alanine -Aspartate -Histidine -Arginine -Glutamine

What are the following substances? -Bisphosphoglycerate mutase -Hexokinase -Pyruvate kinase -Transketolase

scientists studying the principles behing oxygen-hemoglobin dissociation. -They separate the hemoglobin tetramers into individual alpha & beta subunits. -If measured, the oxygen dissociation curve of the dissolved beta subunits will most likely resemble what?

A 2 y/o boy comes to the office by his parents because they notice the boy urine turned black overnight. -Child has no significant past medical history, no medications. -Physical exam: well-nourished child with no swelllin or tenderness of any joints. -Urinalysis: Black urine -Which of the following conversion pathway is most likely deficient in this patient?

3 day old boy comes with poor feeding, vomiting, and progressive lethargy. -Parents stated: "Diaper have burnt sugar smell" -Physical Exam: Lethargic infant with dry mucous membranes and generalized hypertonia. -Which of the following should be restricted from this infant's diet?

74 y/o woman comes with 2 days of left leg pain and numbness. -History of A. Fib & hypertension. -Left lower limb is pale & cold to palpation below the knee. -Ultrasound: occluding thrombus & a left femoral embolectomy is performed. -Post procedure dorsalis pedis & posterior tibial pulses become palpable. -Several hours later, patient feels severe left calf pain, with absent distal pulses. -Physican suspects: injury of the reperfused muscles due to overproduction of reactive oxygen species. -What enzymes is the most likely to help neutralize these toxic molecules?