Metabolism — Flashcards

Flashcard 231: What enzyme converts DHF back to THF? _____

Answer: Dihydrofolate reductase

Flashcard 232: The acetyl-CoA from acetoacetyl-CoA (ketone body metabolism) is used to generate energy via the _____

Answer: Kreb's cycle

Flashcard 233: _____ deficiency results in buildup of adenosine, which is toxic to lymphocytes; causes SCID

Answer: Adenosine deaminase

Flashcard 234: What type of collagen makes up reticulin fibers? _____

Answer: Type III

Flashcard 235: In Purine metabolism, _____ first converts hypoxanthine to xanthine, and then converts xanthine to uric acid

Answer: xanthine oxidase

Flashcard 236: Type II diabetes mellitus is associated with deposition of _____ in the islets of the pancreas

Answer: amylin (islet amyloid polypeptide)

Extra: In Type 2 Diabetes Mellitus, amylin (Islet Amyloid Polypeptide) is co-packaged and co-secreted with insulin. Chronic overproduction leads to its deposition as amyloid within the pancreatic islets, which is a characteristic histopathologic finding.

Flashcard 237: Catecholamine synthesis begins with transport of the amino acid _____ into the nerve terminal

Answer: tyrosine

Extra: Sketchy Pharmacology: Autonomics (Indirect Sympathomimetics)

Flashcard 238: Bcl-2 normally keeps the mitochondrial outer membrane impermeable, thus preventing _____ release from the intermembrane space

Answer: cytochrome c

Flashcard 239: _____ results in the formation of α-(1,6) bonds between glucose molecules

Answer: Branching enzyme

Flashcard 240: _____ glutathione may be converted to _____ glutathione via the enzyme glutathione reductase

Answer: Oxidized