Metabolism — Flashcards

Flashcard 131: Vitamin B7 (biotin) is a cofactor for the enzyme _____ (propionyl CoA metabolism)

Answer: propionyl-CoA carboxylase

Flashcard 132: The _____ of I2 into thyroglobulin is mediated by the enzyme thyroid peroxidase

Answer: organification

Flashcard 133: What does the carrier molecule S-adenosylmethionine (SAM) carry in its activated form? _____

Answer: CH3 groups

Flashcard 134: What is the storage form of vitamin D? _____

Answer: 25-OH D3

Flashcard 135: Deamination of adenine ultimately makes _____

Answer: hypoxanthine

Flashcard 136: In _____ order kinetics, the rate of reaction is constant

Answer: zero

Flashcard 137: The main importance of the cofactor THF (Tetrahydrofolate) is that it can be given a(n) _____ group for use in _____ation reactions

Answer: methyl

Flashcard 138: In extrahepatic tissues, β-hydroxybutyrate may be converted back to _____ via the enzyme β-hydroxybutyrate dehydrogenase

Answer: acetoacetate

Flashcard 139: δ-aminolevulinic acid synthase is regulated via negative feedback by _____ and heme

Answer: glucose

Extra: UWorld:

Flashcard 140: Increased phenylalanine (e.g. in PKU) results in excess _____ in the urine

Answer: phenylketones

Extra: Other: BH4 = tetrahydrobiopterin