Metabolism — Flashcards

Flashcard 1221: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder resulting in reduced _____ of G6PD

Answer: half-life

Flashcard 1222: What is the shared structural feature of amyloid?

Answer: Beta-pleated sheet

Extra: All amyloid deposits, regardless of the precursor protein, share a common **cross-beta-pleated sheet** secondary structure. This structural feature is responsible for the characteristic apple-green birefringence when viewed under polarized light after staining with Congo red.

Flashcard 1223: Which two amino acids do protein kinase A and protein kinase C phosphorylate to continue the signaling cascade?_____

Answer: serine & threonine

Flashcard 1224: One type of receptor tyrosine kinase is a _____, which dimerizes and auto-phosphorylates upon binding of a hormone or ligand

Answer: monomer

Flashcard 1225: If G for a reaction is _____ than zero, the reaction happens spontaneously

Answer: less

Flashcard 1226: What ion is required by cadherin proteins in epithelial cell junctions?_____

Answer: Ca2+

Flashcard 1227: While thyroid hormone increases both protein synthesis and degradation, the overall effect of thyroid hormone is _____

Answer: catabolic

Flashcard 1228: If G for a reaction is _____ than zero, energy must be added for the reaction to occur

Answer: greater

Flashcard 1229: Methionine is combined with adenosine (using ATP) to form _____

Answer: S-adenosylmethionine (SAM)

Flashcard 1230: In the following group of diseases, what is the most likely ratio of conjugated bilirubin : total bilirubin? - Gilbert Syndrome / Crigler-Najjar - Physiologic Jaundice of Newborn - Hemolysis Answer: _____ %

Answer: < 20%