Metabolism — Flashcards

Flashcard 1201: Some of the hemoglobin in the blood due to intravascular hemolysis is returned to the spleen by _____ molecules

Answer: haptoglobin

Flashcard 1202: After complete metabolism, what is the total amount of ATP (or GTP) produced from 1 round of the Krebs' cycle? _____

Answer: 10 ATP equivalents

Flashcard 1203: Biliary tract infections may cause pigment gallstones by _____ bilirubin, which increases risk of precipitation

Answer: deconjugating

Flashcard 1204: What is the major source of energy during the first 2 - 7 seconds of exercise? _____

Answer: Creatine phosphate

Flashcard 1205: A hemo-globin molecule has the potential to bind _____ O2 molecule(s)

Answer: 4

Flashcard 1206: The Michaelis-Menten constant, Km is _____ proportional to the affinity of the enzyme for its substrate

Answer: inversely

Flashcard 1207: While thyroid hormone increases both protein synthesis and degradation, the overall effect of thyroid hormone is _____

Answer: catabolic

Flashcard 1208: What is the most common vitamin deficiency in the U.S.?_____

Answer: Folate (vitamin B9)

Flashcard 1209: Factor XI of the coagulation cascade is activated by factor _____

Answer: XIIa

Flashcard 1210: What is the shared structural feature of amyloid?

Answer: Beta-pleated sheet

Extra: All amyloid deposits, regardless of the precursor protein, share a common **cross-beta-pleated sheet** secondary structure. This structural feature is responsible for the characteristic apple-green birefringence when viewed under polarized light after staining with Congo red.