Metabolism — Flashcards

Flashcard 1081: What is the level of aldosterone in 17-hydroxylase deficiency? _____

Answer: Decreased!

Flashcard 1082: Vitamin _____ deficiency can result in metaplasia

Answer: A

Flashcard 1083: HGPRT deficiency (Lesch-Nyhan syndrome) results in _____ de novo purine synthesis

Answer: increased

Flashcard 1084: Can red blood cells use ketones for energy? Why? _____

Answer: No, they lack mitochondria

Flashcard 1085: A deficiency in _____ is the most common genetic cause of hyperhomocysteinemia (homocystinuria II)

Answer: methylene tetrahydrofolate reductase (MTHFR)

Flashcard 1086: Is conjugated (direct) bilirubin water soluble?_____

Answer: Yes

Flashcard 1087: Through which secondary messenger does ANP exert its actions?_____

Answer: cGMP

Flashcard 1088: Inside the cells of the PCT, H2O and CO2 are converted back into _____

Answer: H2CO3

Flashcard 1089: Through which secondary messenger(s) does glucagon exert its actions on liver and adipose tissue?_____

Answer: cAMP

Flashcard 1090: What is the molecular shorthand for **reduced glutathione**?

Answer: GSH (Glutathione-SH)

Extra: Reduced glutathione (GSH) contains a sulfhydryl group. Two molecules of GSH are oxidized to form **GSSG** (oxidized glutathione), which contains a disulfide bond.