Safe Prescribing UK Medical PG Flashcards - Medical Study Cards
Master Safe Prescribing with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Safe Prescribing Flashcard Deck - 10 Cards
Flashcard 101: The management of autonomic instability in serotonin syndrome involves treatment with _____ antihypertensives (e.g. esmolol or nitroprusside).
Answer: short-acting
Extra: Serotonin Syndrome management:
1. Discontinue offending agents.
2. Supportive care (IV fluids, oxygen).
3. Benzodiazepines for agitation and seizures.
4. Cyproheptadine (5-HT2A antagonist) as a specific antidote.
5. Hyperthermia: aggressive cooling (not antipyretics).
6. Autonomic instability: treat with short-acting antihypertensives; avoid monoamine oxidase inhibitors.
Flashcard 102: _____ should be monitored closely in digoxin toxicity
Answer: Potassium
Flashcard 103: What class of prescription medications most commonly causes serotonin syndrome?
_____
Answer: Antidepressants (e.g. MAOIs, SSRIs)
Flashcard 104: Administration of _____ serotonergic drugs simultaneously may result in serotonin syndrome
Answer: multiple
Flashcard 105: Severe digoxin toxicity can cause heart _____, heart failure and cardiac arrhythmias
Answer: block
Flashcard 106: Digibind (digoxin-specific antibody fragments) will _____ potassium levels when administered. Therefore, target levels prior to administration should be on the upper level of normal
Answer: lower
Flashcard 107:
The presentation of serotonin syndrome can be remembered by the mnemonic:
_____
Answer: HAHA:
•
H: Hyperthermia
•
A: Autonomic dysfunction
•
H: Hyperreflexia
•
A: Altered mental status
Flashcard 108: The management of severe/refractory serotonin syndrome involves _____
Answer: cyproheptadine
Flashcard 109: Serotonin syndrome may present with hyperthermia & hyperreflexia due to _____
Answer: neuromuscular excitability
Flashcard 110: Patients with TCA toxicity are at risk of neurological sequelae including _____ and coma
Answer: seizures
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