Rheumatology & Haematology — Flashcards

Flashcard 671: The most common site of _____ involvement in lymphoma is the Gastrointestinal (GI) tract (specifically the stomach)

Answer: extranodal

Extra: Primary sites of lymphoma are the lymph nodes. When it occurs outside the nodes (extranodal), the GI tract is #1, followed by the skin. The spleen and liver are common sites of systemic involvement (stage IV disease) but not the most common extranodal sites overall.

Flashcard 672: Multiple myeloma most commoly occurs in _____

Answer: the elderly (60-70)

Flashcard 673: _____ can be used as a prognostic indicator in Hodgkin's lymphoma

Answer: LDH

Flashcard 674: _____% of Hodgkin's lymphoma is associated with EBV infection

Answer: 40

Flashcard 675: Lymphomas commonly present with _____, B symptoms and pruritus

Answer: unexplained lymphadenopathy

Flashcard 676: The clinical features of myeloma can be memorised using the _____ mnemonic.

Answer: CRAB

Extra: Clinical features of Multiple Myeloma (CRAB): - **C**: Calcium (Hypercalcaemia) - **R**: Renal insufficiency - **A**: Anemia - **B**: Bone lesions (Lytic lesions, fractures)

Flashcard 677: Myeloma may cause decreased production of _____ which leads to an increased susceptibility to infection

Answer: normal immunoglobulins

Flashcard 678: Multiple myeloma is a cancer of the _____ cells

Answer: plasma

Flashcard 679: FBC in a patient with Hodgkin's lymphoma may show _____, lymphocytopenia and eosinophilia

Answer: normocytic, normochromic anaemia

Flashcard 680: 60% of Hodgkin's lymphoma has _____ or mediastinal lymph node involvement

Answer: cervical