Rheumatology & Haematology — Flashcards

Flashcard 681: The diagnostic investigation for Hodgkin's lymphoma is _____

Answer: lymph node excision biopsy

Flashcard 682: Which lymphoma classically presents with a bimodal age distribution, often affecting younger patients? \n_____

Answer: Hodgkin's lymphoma

Extra: Hodgkin Lymphoma typically shows a **bimodal age distribution**, with the first peak in young adults (ages 15–35) and a second peak in older adults (>55 years). In contrast, most Non-Hodgkin Lymphomas increase in incidence steadily with age.

Flashcard 683: Hodgkin's lymphoma has a _____ incidence, with the peak incidence occuring in patients aged 20-30 years

Answer: bimodal

Flashcard 684: Myeloma patients at risk of infection may be given _____

Answer: prophylactic antibiotics

Flashcard 685: Immunoglobulin light chains in the urine of a patient with myeloma are known as _____

Answer: Bence-Jones proteins

Flashcard 686: Myeloma may cause hypercalcaemia due to increased _____ activity which results in osteolytic lesions

Answer: osteoclast

Flashcard 687: _____ of patients with MGUS go on to develop Myeloma

Answer: 1%

Flashcard 688: Myeloma is a _____ disease - there is no cure

Answer: relapsing / remitting

Flashcard 689: Induction therapy prior to stem cell transplantation in myeloma involves a combination of: 1. _____ 2. Chemotherapy (e.g. cyclophosphamide) 3. Steroids (e.g. dexamethasone)

Answer: Targeted immunomodulatory drugs (e.g. thalidomide or bortezomib)

Flashcard 690: _____ may be found upon X-ray of the skull in myeloma patients

Answer: Rain-drop skull