Rheumatology & Haematology — Flashcards

Polycythaemia vera is variable but typically occurs in ages >_____ years

Accelerated phase of CML presents with fatigue because of _____

_____ phase of CML presents with hyperviscosity syndrome because of the significantly ↑↑ number of cells (blasts, granulocytes)

The t(_____;22) translocation generates a(n) BCR-ABL fusion protein with increased tyrosine kinase activity in chronic myeloid leukaemia

Chronic myeloid leukaemia is a _____ disorder

What is the initial investigation for polycythaemia vera? _____

Which form of polycythaemia is associated with lung disease (e.g. COPD / obstructive sleep apnea), congenital heart disease, high altitude, or low birth weight? _____

_____ is a myeloproliferative disorder that leads to erythrocytosis with or without granulocytosis & thrombocytosis

Polycythemia vera may present with _____ due to excessive RBCs causing tissue congestion

Hint: visible cutaneous finding

Chronic myeloid leukaemia is often diagnosed _____ on a FBC