Rheumatology & Haematology — Flashcards

What is the most common blood transfusion reaction? _____

Direct antiglobluin (Coombs) test _____ = febrile non-haemolytic transfusion reaction Direct antiglobluin (Coombs) test +ve = acute haemolytic transfusion reaction

_____ is a neoplastic proliferation of mature myeloid cells, especially megakaryocytes that activate fibroblasts

What physical exam finding can distinguish myelofibrosis from aplastic anemia? _____

What condition is associated with increased risk for anaphylactic reaction when receiving blood transfusions? _____

Blood transfusion reactions 1) _____ 2) Transfusion associated circulatory overload (TACO) 3) Delayed haemolytic transfusion reaction 4) Acute haemolytic transfusion reaction 5) Transfusion-related acute lung injury (TRALI) 6) Anaphylactic transfusion reaction

Hint: most common

What is the management of acute haemolytic transfusion reactions? _____

Which blood transfusion reaction is caused by donor anti-leukocyte antibodies against recipient neutrophils and pulmonary endothelial cells? _____

What is the management of minor allergic transfusion reaction (urticaria, no signs of anaphylaxis)? _____

What is the likely diagnosis in a patient that develops fever / chills, flank pain, haemoglobinuria, and DIC within 1 hour after starting RBC tranfusion? _____

Hint: diagnosis?