Rheumatology & Haematology — Flashcards

What are the initial investigations for myelofibrosis? _____

Hint: 2

Which blood transfusion reaction can be caused by accumulation of cytokines from donor WBC -or- type II HSR with host antibodies against donor HLA/WBCs? _____

Direct antiglobluin (Coombs) test _____ = febrile non-haemolytic transfusion reaction Direct antiglobluin (Coombs) test +ve = acute haemolytic transfusion reaction

_____ is a neoplastic proliferation of mature myeloid cells, especially megakaryocytes that activate fibroblasts

What blood transfusion is the most common cause of death? _____

What is the definitive management of myelofibrosis? _____

What is the management of acute haemolytic transfusion reactions? _____

What is the first step in management for any blood transfusion reaction? _____

Which blood transfusion reaction is caused by donor anti-leukocyte antibodies against recipient neutrophils and pulmonary endothelial cells? _____

What is the management of minor allergic transfusion reaction (urticaria, no signs of anaphylaxis)? _____