Rheumatology & Haematology — Flashcards

_____ is a myeloproliferative disorder that leads to bone marrow fibrosis, extramedullary haematopoiesis, & splenomegaly

Which blood transfusion reaction is a reaction against donor plasma proteins in transfused blood? _____

What is the likely diagnosis in a patient that develops respiratory distress, hypertension, tachycardia and signs of a heart failure 6-12 hours after a RBC transfusion? _____

Hint: diagnosis?

What blood transfusion is the most common cause of death? _____

_____ myelofibrosis occurs as a result of disease progression in patients with previously diagnosed myeloproliferative disorder (e.g. PV, ET)

What are the bone marrow aspiration finding(s) for myelofibrosis? _____

What is the likely diagnosis in a patient with respiratory distress, hypotension, and noncardiogenic pulmonary oedema up to 6 hours after a blood transfusion? _____

Hint: diagnosis?

Myelofibrosis can present with _____ splenomegaly

What is the recommended RBC pre-treatment for a patient who will receive a RBC transfusion and has a history of febrile non-hemolytic transfusion reaction? _____

Which blood transfusion reaction can be caused by accumulation of cytokines from donor WBC -or- type II HSR with host antibodies against donor HLA/WBCs? _____