Rheumatology & Haematology — Flashcards

In sickle cell disease antibiotic prophylaxis with _____ is given at ages >3months until 5 years old (or lifelong)

Sickle cell disease can cause _____ due to vaso-occlusion of cerebral vessels

Vaso-occlusive crisis presents with _____ to an affected area (e.g. limbs, chest, back) for several hours up to ~7 days

In sickle cell disease, the spleen becomes dysfunctional in _____ ("splenic fatigue")

Hint: demographic

Sickle cell disease will likely cause chronic _____ presenting with persistent fatigue, pallor, & delayed growth in children

Suspect _____ in patients with sickle cell disease that have LUQ tenderness, hypovolaemic shock, & splenomegaly

Patients with sickle cell disease are given _____ to prevent infection with encapsulated organisms

What is the confirmatory diagnosis of sickle cell disease? _____

Acute haemolytic crisis in sickle cell disease may require _____

Hint: management

_____ is the most common cause of osteomyelitis in patients with sickle cell disease