Rheumatology & Haematology — Flashcards

Vaso-occlusive crisis is also known as _____ crisis

What is the likely diagnosis in an African American infant that presents with symmetric swelling/tenderness of the bilateral hands and feet? _____

Hint: diagnosis?

What is the initial general management for vaso-occlusive crisis/events? _____

What is the most common acute complication/event in sickle cell disease? _____

Sickle cell trait presents _____, unless in severe conditions

The sickle cell allele / HbS provides protection against _____, which likely explains the high prevalence in Africans

_____ in sickle cell disease is accelerated destruction of sickled RBC leading to worsening anaemia, jaundice, & ↑ bilirubin

Patients with sickle cell disease are given _____ to prevent infection with encapsulated organisms

Sickle cell disease can cause _____ due to vaso-occlusion in the pulmonary vasculature

Vaso-occlusive crisis is _____ of tissue secondary to microvascular occlusion from sickled RBCs