Rheumatology & Haematology — Flashcards

What are the major causes of acute severe anaemia in sickle cell disease? _____: ↓ reticulocyte count + no splenomegaly Splenic sequestration (Vaso-occlusion): ↑ reticulocyte count + splenomegaly

In sickle cell disease antibiotic prophylaxis with _____ is given at ages >3months until 5 years old (or lifelong)

Suspect _____ in patients with sickle cell disease that have chest pain, fever, dyspnoea, & lung infiltrates

Sickle cell disease can cause _____ that involves splenic vaso-occlusion and pooling of large amounts of blood in the spleen

One consequence of autosplenectomy in sickle cell disease is increased risk of infection with _____ organisms

Sickle cell trait presents _____, unless in severe conditions

Sickle cell anaemia has _____ reticulocyte count

Hint: ↓/↑

Sickle cell disease can present as _____ in the male sex organ

Patients with sickle cell disease are given _____ to prevent infection with encapsulated organisms

_____ is considered in severe vaso-occlusive crisis/events, e.g. acute chest syndrome or stroke

Hint: Management