Rheumatology & Haematology — Flashcards

Sickle cell disease can cause _____ that involves splenic vaso-occlusion and pooling of large amounts of blood in the spleen

Vaso-occlusive crisis is also known as _____ crisis

Sickle cell disease can present as _____ in the male sex organ

Sickle cell trait presents _____, unless in severe conditions

What are the major causes of acute severe anaemia in sickle cell disease? _____: ↓ reticulocyte count + no splenomegaly Splenic sequestration (Vaso-occlusion): ↑ reticulocyte count + splenomegaly

What is the most common acute complication/event in sickle cell disease? _____

Sickle cell disease can be complicated with _____ from encapsulated organisms causing sepsis, pneumonia, & meningitis

What is the initial general management for sickle cell disease acute crisis? _____ Hydration Oxygen Blood transfusions to manage severe anaemia, stroke, & acute chest syndrome Antibiotics for infection

Patients with sickle cell disease are given _____ to prevent infection with encapsulated organisms

Sickle cell disease often has persistent, mild _____cytic anaemia on FBC