Rheumatology & Haematology — Flashcards

Management of beta thalassemia major involves chronic _____, which increases risk for secondary hemochromatosis

Public Health England recommend all _____ women are screened for thalassaemia

What is the most accurate investigation for haemophilia? _____

Beta thalassaemia _____ is due to β0/β0 and presents with severe anaemia that is transfusion-dependent

What are the initial investigations for suspected haemophilia? _____

Hint: 2

Haemophilias present with _____ commonly affecting the knees, ankles, & elbows; recurrent ecchymoses; and prolonged haemorrhage particularly after surgery/procedures

Blood smear in thalassaemia is associated with _____ cells

_____ is a neoplastic proliferation of mature myeloid cells, especially platelets

Beta thalassaemia _____ and sickle cell anemia are characterised by expansion of haematopoiesis into facial bones, leading to "chipmunk facies"

_____ in sickle cell disease is accelerated destruction of sickled RBC leading to worsening anaemia, jaundice, & ↑ bilirubin