Rheumatology & Haematology — Flashcards

Beta thalassaemia _____ is due to β+/β+ or β+/β0 and presents with moderate anaemia

Patients with thalassaemias will be offered genetic _____ and family members will be offered screening

Beta thalassaemia _____ is due to β0/β0 and presents with severe anaemia that is transfusion-dependent

What is the management for asymptomatic thalassaemias? _____

Haemophilia B is an _____ pattern of inheritance

Haemophilia A, B, and C disrupts the _____ coagulation pathway

Hemoglobin A (HbA) is composed of _____ α-globin chains and _____ β-globin chains.

Suspect _____ in patients with sickle cell disease that have chest pain, fever, dyspnoea, & lung infiltrates

The sickle cell allele / HbS provides protection against _____, which likely explains the high prevalence in Africans

One consequence of autosplenectomy in sickle cell disease is increased risk of infection with _____ organisms