Gastroenterology & Hepatology — Flashcards

Flashcard 471: What is the mainstay investigation to diagnose hepatitis C? _____ → HCV RNA (if anti-HCV antibody test is +ve)

Answer: Anti-HCV antibodies

Flashcard 472: If a case of hepatitis C is suspected then notify _____

Answer: Public Health

Flashcard 473: Type _____ autoimmune hepatitis antibodies are anti-soluble liver antigens (anti-SLA) ± liver-pancreas antigen (anti-LP)

Answer: 3

Flashcard 474: Autoimmune hepatitis can present with _____ in ~40% of patients and ~30% have cirrhosis at the time of presentation

Answer: jaundice

Flashcard 475: Autoimmune hepatitis is associated with other autoimmune diseases, most commonly _____

Answer: autoimmune thyroid disease

Flashcard 476: Active management for _____ hepatitis B is entecavir or tenofovir

Answer: chronic

Extra: Acute Hepatitis B is usually managed supportively. Antivirals are indicated for chronic HBV (based on DNA levels, ALT, and cirrhosis status) or in cases of fulminant acute HBV.

Flashcard 477: What is the mainstay specialist management of hepatitis C?\n_____

Answer: Identify HCV genotyping, presence or absence of cirrhosis, then treat with direct-acting antivirals (DAAs)

Flashcard 478: _____ hepatitis C < 6 months Chronic hepatitis C > 6 months after initial infection

Answer: Acute

Flashcard 479: What is the definitive management of fulminant hepatitis?

Answer: Liver transplant is the only definitive treatment for patients who do not show spontaneous recovery, as mortality rates exceed 80% in many cases.

Flashcard 480: Type _____ autoimmune hepatitis is the most common (70-80%)

Answer: 1