Gastroenterology & Hepatology — Flashcards

Flashcard 471: What is the mainstay specialist management of hepatitis C?\n_____

Answer: Identify HCV genotyping, presence or absence of cirrhosis, then treat with direct-acting antivirals (DAAs)

Flashcard 472: _____ hepatitis C < 6 months Chronic hepatitis C > 6 months after initial infection

Answer: Acute

Flashcard 473: Type _____ autoimmune hepatitis antibodies are anti-nuclear antibodies (ANA) ± anti-smooth muscle antibodies (SMA)

Answer: 1

Flashcard 474: How do you diagnose autoimmune hepatitis? _____ -ve test for viral hepatitis High titers of autoantibodies + clinical findings

Answer: LFTs → raised ALT & AST

Flashcard 475: The main types of autoimmune hepatitis are _____, type 2, & type 3

Answer: type 1

Flashcard 476: Type _____ autoimmune hepatitis antibodies are anti-liver kidney microsomal-1 (LKM-1) ± anti-liver cytosolic-1 (LC-1)

Answer: 2

Flashcard 477: How is hepatitis C transmitted? _____ Pre 1991 it was spread through blood transfusions

Answer: Through infected blood via needles

Flashcard 478: Patients with autoimmune hepatitis should be vaccinated against _____ & B

Answer: hepatitis A

Flashcard 479: There are 2 main types of hepatitis C; _____ & Chronic

Answer: Acute

Flashcard 480: What is the mainstay management of autoimmune hepatitis? _____

Answer: Corticosteroids (e.g., prednisolone) +/- Azathioprine

Extra: The goal of treatment is to induce and maintain remission. Prednisolone is used for induction, while Azathioprine is often added as a steroid-sparing agent for maintenance.