Psychopharmacology — Flashcards

Flashcard 11: Where are the electrodes placed in ECT?_____

Answer: Bifrontotemporal, right unilateral

Flashcard 12: Do patients with atypical depression respond effectively to treatment with MAOIs and SSRIs?_____

Answer: Yes

Flashcard 13: _____ intracranial tension is a relative contraindication for electroconvulsive therapy (ECT).

Answer: Increased

Flashcard 14: Clozapine should be discontinued if the absolute neutrophil count (ANC) drops below _____ cells/µL.

Answer: 500

Flashcard 15: In _____, the patient takes additional doses of the drug, without realizing it, which may lead to accidental poisoning

Answer: Drug automatism

Flashcard 16: Between TMS and ECT, which requires a shorter treatment course?

Answer: ECT

Flashcard 17: What is the first-line pharmacotherapy for major depressive disorder (MDD) with psychotic features?

Answer: Combination of an **antidepressant** (usually an SSRI) and an **antipsychotic** (usually a second-generation antipsychotic)

Extra: Electroconvulsive therapy (ECT) is also a first-line treatment option, especially for severe cases, high suicide risk, or when rapid response is required. TCAs are generally not first-line due to their side-effect profile compared to SSRIs.

Flashcard 18: _____ combined with ECT has been shown to cause prolonged seizures(lasting more than 180 secs) and increased post ictal delirium in electroconvulsive therapy.

Answer: Lithium

Flashcard 19: What is the mechanism of action of electroconvulsive therapy?

Answer: Neuroplasticity

Flashcard 20: _____ is a mood stabilizer with an antisuicidal role.

Answer: Lithium