Endocrinology — Flashcards

The hormone sensitivity (responsiveness) of a target tissue may be changed in two ways: 1. Change the _____ of receptors 2. Change the affinity of receptors

The main functions of thyroid hormone can be remembered with the "6 B's": 1. _____ 2. Bone growth 3. Beta-adrenergic effects 4. Basal metabolic rate (increased) 5. Blood sugar (increased) 6. Break down lipids

Glucocorticoids _____ glucose utilization by tissues and decrease insulin sensitivity of adipose tissue

The effects of cortisol may be remembered with the mnemonic "A BIG FIB": A: _____B: Blood pressure (increased, via alpha1)I: Insulin resistance (increased)G: Gluconeogenesis (increased)F: Fibroblast activity (decreased)I: Inflammatory/Immune response (decreased)B: Bone formation (decreased)

In bone, 1,25-(OH)2 D3 acts syngergistically with PTH to stimulate _____ activity and bone resorption

One major effect of thyroid hormone is increased _____ with a resultant increase in BMR and body temperature, due to increased Na/K+-ATPase activity

Activation of _____ adrenergic receptors on pancreatic islet cells causes decreased insulin release

Obesity _____ the conversion of T4 to T3, thus increasing the amount of active hormone

In bone, PTH receptors are located on _____, but not on osteoclasts

Glucagon-like peptide-1 (GLP-1) stimulates _____ secretion and inhibits glucagon secretion