Endocrinology — Flashcards

Increased ATP:ADP ratio in the pancreatic beta cell (as a result of glucose metabolism) causes ATP-sensitive _____ channels to close, causing membrane depolarization

_____ puberty, excessive levels of growth hormone cause gigantism (increased linear growth)

PTH action causes increased urinary _____ and phosphat-uria

The _____ cells of the islets of Langerhans compose 65% of the islet and secrete insulin

Chronic excess levels of cortisol (glucocorticoid) result in decreased levels of _____ and ACTH via negative feedback

Vasopressin (ADH) causes _____ of arterioles by activating V1 receptors

Thyroid, Pituitary, & Adrenal _____ stimulates the liver to produce IGF-1

High levels of _____ inhibit organification of I2, and therefore inhibit synthesis of thyroid hormones (Wolff-Chaikoff effect)

The main functions of thyroid hormone can be remembered with the "6 B's": 1. _____ 2. Bone growth 3. Beta-adrenergic effects 4. Basal metabolic rate (increased) 5. Blood sugar (increased) 6. Break down lipids

Tissues that are not dependent on insulin for glucose uptake may be remembered using the mnemonic "BRICK LIPS":B: _____R: RBCsI: IntestineC: CorneaK: KidneyL: LiverI: Islet (Beta) cellsP: PlacentaS: Spermatocytes