Hormone Receptors and Signaling — Flashcards

The hormone sensitivity (responsiveness) of a target tissue may be changed in two ways: 1. Change the _____ of receptors 2. Change the affinity of receptors

_____ increase binding of thyroxine to thyroxine binding globulin

Hint: Hormone

Thyroid hormone increases the processes of _____, gluconeogenesis, proteolysis, and lipolysis, all of which may provide sources of ATP

How is the action of peptide hormones terminated?_____

Depolarization of the pancreatic beta cell causes voltage-sensitive _____ channels to open, causing an increase in intracellular Ca2+

Binding of atrial natriuretic peptide to its receptor guanylyl cyclase causes conversion of _____ to cGMP

_____ (hormone) inhibit apoptosis in osteoblasts and induce apoptosis in osteoclasts.

The parathyroid glands have _____ receptors that negatively regulate secretion of PTH

Calcitriol _____ Ca2+ and phosphate release into the bloodstream by stimulating osteoblasts to activate osteoclasts

Prolactin deficiency occurs with destruction of the _____ and results in the failure to lactate (females)