Endocrine Pharmacology — Flashcards

Flashcard 131: _____ acts as a cathepsin-K inhibitor which is an enzyme in osteoclast that facilitates bone resorption.

Answer: Odanacatib

Flashcard 132: _____ is contraindicated in patients with prior history of radiation, for treatment of osteoporosis.

Answer: Teriparatide

Flashcard 133: In the management of a patient with thyroid storm, _____ is given first, followed by _____ one hour later.

Answer: propylthiouracil (PTU); potassium iodide

Flashcard 134: _____ is a synthetic derivative of 19-nortestosterone used as Add back therapy for Fibroid

Answer: Tibolone

Flashcard 135: _____ can cause euglycemic diabetic ketoacidosis (DKA)

Answer: SGLT2 inhibitors::OHA

Flashcard 136: Drug of choice as antidiabetic in obese patient:

Answer: Metformin

Flashcard 137: Drug of choice in nocturnal enuresis is

Answer: Desmopressin

Flashcard 138: Drug of choice for acute adrenal insufficiency is?

Answer: Hydrocortisone

Flashcard 139: Drug of choice for hyperthyroidism during 2nd and 3rd trimester of pregnancy is:

Answer: Methimazole

Extra: • 1st trimester DOC: Propylthiouracil (PTU) - used during organogenesis to avoid Methimazole embryopathy (e.g., aplasia cutis). • 2nd and 3rd trimester DOC: Methimazole - preferred for the remainder of pregnancy to avoid the risk of PTU-induced severe hepatotoxicity.

Flashcard 140: Drug of choice for central diabetes insipidus

Answer: Desmopressin