Clinical Pharmacology and Drug Toxicity — Flashcards

_____ is the primary mutagenic metabolite that causes bladder cancer in patients exposed to cyclophosphamide

Category _____: Strong risk of birth defects

Category _____: Shown side effects in animal models, or where inadequate animal and human studies are available

Is the agranulocytosis due to clozapine dose dependent?_____

_____ is associated with dose-dependent and concentration-dependent orthostatic hypotension.

Why is physostigmine not recommended in management of TCA toxicity?_____

What is the side effect associated with Camostat mesylate?_____

Which prokinetic drug is associated with significant risk of QT prolongation?_____

Busulfan causes _____ subcapsular cataract

Which antidepressants are safest to give during pregnancy?_____