Clinical Pharmacology and Drug Toxicity — Flashcards

A negative _____ test and two forms of contraception are required before isotretinoin (vitamin A) is prescribed

_____ are a group of penicillins that can cause the severe side-effect, Stevens-Johnson syndrome

Neuro/Psych _____ is an anti-epileptic that rarely causes a fatal hepatotoxicity

Cocaine intoxication can cause agitation, _____ (BP), tachycardia (HR), and pupillary dilation

Aminoglycosides can lead to severe decreases in _____ serum concentration, which in prolonged use can eventually precipitate tetany

Pyrazinamide is _____-toxic, even leading to liver necrosis

Prolonged use of the _____ drug has been implicated in subacute myelo-optic neuropathy (SMON).

Hint: antiluminal

Acetazolamide may promote the formation of _____ kidney stones (favored by alkaline urine).

Linezolid is a weak _____ inhibitor, thus predisposing patients to serotonin syndrome

_____ and aplastic anemia are rare hematological complications of propylthiouracil and methimazole use.