Neuropathology — Flashcards

In response to axon damage, the neuron cell body undergoes _____, which is the swelling of the cell body and dispersion of Nissl substance (chromatolysis)

_____ is characterized grossly by gray-appearing plaques in the white matter

Enlargement of the nucleus to two to five times the normal size in Schwann cells of the dorsal root ganglia and peripheral nerves, also called as _____ is seen in ataxia-telangiectasia

_____ are microscopic nodular collections of glial cells at abnormal locations, often in the superficial and deep layers of cerebral cortex seen in neurofibromatosis type 2

Cerebral ischemia of the neocortex typically affects layers _____, 5, and 6, causing cortical laminar necrosis

Progressive multifocal leukoencephalopathy is characterized by destruction of _____ and astrocytes; typically in the parietal and occipital areas

_____ is a primary CNS tumor characterized histologically by "fried egg" cells with a "chicken-wire" capillary pattern

_____ disease is characterized histologically by Lewy bodies, which are round, eosinophilic inclusions composed of alpha-synuclein

Bacterial meningitis may lead to high pressure hydrocephalus, _____ (most common sequelae), and seizures, secondary to fibrosis

_____ hemorrhage most commonly occurs due to rupture of Charcot-Bouchard microaneurysms, secondary to chronic hypertension