Neuropathology — Flashcards

Flashcard 151: Tuberculous caseous foci in brain, meninges and spinal cord is known as _____ focus.

Answer: Rich

Flashcard 152: Myxopapillary ependymomas are classified under WHO grade _____ tumors

Answer: 2

Extra: Note: Myxopapillary ependymoma was reclassified from WHO Grade 1 to **WHO Grade 2** in the 2021 WHO Classification of Tumors of the Central Nervous System (5th Edition) because its clinical behavior and risk of recurrence are more aligned with Grade 2 tumors.

Flashcard 153: Transverse section of nerve shows cut onion appearance first in _____ leprosy

Answer: borderline (BB)

Flashcard 154: Focal collections of cells mimicking the appearance of Meissner corpuscles (pseudo-Meissner corpuscles) are seen in _____

Answer: diffuse neurofibroma

Flashcard 155: Preferential involvement of the subcortical U fibers early on is characteristic of which demyelinating disease?_____

Answer: Canavan disease

Flashcard 156: Mutations in the gene encoding LRRK2 (leucine-rich repeat kinase 2) are a common cause of autosomal dominant _____

Answer: Parkinson's disease

Flashcard 157: _____ is one of the commonest infratentorial tumors in childhood

Answer: Pilocytic astrocytoma

Flashcard 158: What is the gold standard for the diagnosis of Pure Neuritic Leprosy?

Answer: Nerve biopsy

Flashcard 159: In chronic cases of Korsakoff's psychosis, there will be atrophy of the _____.

Answer: mamillary bodies

Flashcard 160: Pick bodies are inclusions that stain strongly with _____ stain.

Answer: silver