Molecular Pathology — Flashcards

HER2-_____ cancers are most common subtype of breast cancer in patients with germline mutations in TP53 (Li Fraumeni syndrome)

The only Hep. B viral gene product that is consistently present in the tumor cells arising from chronic Hep. B infections is the _____.

_____ is a molecular test in breast cancer that is a 21-gene assay

miR-_____ is overexpressed in many human B-cell lymphomas

In Array based Comparative Genomic Hybridization, if the test sample has deletion, then some spots on the array will flouresce _____

Loss-of-function mutations in _____ have been specifically associated with bicuspid aortic valve in certain families

What gene inactivation is associated with anaplastic carcinoma of thyroid?_____

The number of _____ bodies is one lesser than the number of X chromosomes.

Muir-Torre syndrome is associated with mutations in DNA _____ repair genes

Translocation in Philadelphia chromosome is best studied by using _____