Molecular Pathology — Flashcards

Mutations in MYCL1 can cause _____ Carcinoma due to a resultant amplification of the transcription factors activity (nuclear regulator)

What point mutations in the HFE gene are typically seen with primary hemochromatosis? _____ (more common) and H63D

The _____ instability pathway of colorectal cancer is characterized by mutations or methylation of mismatch repair genes

Hirschsprung disease is associated with _____ mutations in the RET gene

What is the mechanism that results in malignancy from the cyclin D1 oncogene?_____

What translocation is most commonly associated with infantile leukemia?_____

What is the mechanism that results in malignancy from the ABL oncogene?_____

Mutations in MYCN (MIC-2) can cause _____ due to a resultant amplification of the transcription factors activity (nuclear regulator)

_____ is a protein from high-risk HPV that binds to p53.

What is the mechanism that results in malignancy from the c-MYC oncogene?_____