Inflammation and Repair — Flashcards

Important neutrophil chemotactants include: a. C5a b. IL-8 c. LTB4 d. _____ e. platelet-activating factor

_____ and serotonin are among the first mediators to be released during inflammation

Fever in inflammation is mediated by release of _____, TNF and IL-6 by macrophages in response to pyrogens (e.g. LPS from bacteria)

In the setting of chronic inflammation, macrophages can be activated to M1 macrophages by stimulation from _____ cells, resulting in a proinflammatory phenotype

During leukocyte margination, leukocytes marginate from the _____ of flow to the periphery (center or periphery)

A _____ lies beneath an intact epidermis and consists of an extravascular collection of blood that has leaked from blood vessels damaged by mechanical impact

_____ produce major basic protein, which destroys parasites and is responsible for epithelial cell damage in asthma

Acute inflammation arises in response to _____ or tissue necrosis

Toluidine blue is the special stain for _____ cells.

The most common mechanism of vascular leakage in acute inflammation is the _____ of endothelial cells