Immunopathology — Flashcards

What HLA subtypes are associated with Graves disease? _____ and DR3

Inflammation in _____-myositis is mediated by CD-8+ T cells

_____ cells are plasma cells characterized by the accumulation of multiple Russell bodies

Isolated IgA deficiency is associated with deficiency of IgG subtypes IgG_____ and IgG4.

Defective _____ interactions can cause autoimmune lymphoproliferative syndrome

_____ disease is characterized by recurrent infection and granuloma formation with catalase-positive organisms

Tumor cells evade CD_____ T-cell immune surveillance by down-regulating MHC I expression

_____ and centromeric pattern of staining is seen in systemic sclerosis

Definite diagnosis of IgG4-RD may be made by demonstrating IgG4 level exceeding _____ mg/dL, or >10 IgG4+ plasma cells per high-power field and an IgG4+:IgG+ plasma cell ratio of at least 40% on histologic tissue section

Immunodeficiences with decreased _____-cells tend to produce recurrent viral and fungal infections