Hematology — Flashcards

Flashcard 61: Major clinical manifestations of GVHD result from the involvement of the immune system and epithelia of the skin, _____, and intestine

Answer: liver

Flashcard 62: The causes of eosinophilia may be remembered with the mnemonic "PACCMAN": P: _____A: asthmaC: Churg-Strauss syndromeC: chronic adrenal insufficiencyM: Myeloproliferative disordersA: allergic processesN: neoplasia (ex. Hodgkin lymphoma)

Answer: parasites

Flashcard 63: Due to Streptococcus pneumoniae having a polysaccharide capsule virulence factor, patients who have _____ disease or a-splenic patients are particularly susceptible

Answer: sickle cell

Flashcard 64: Multiple myeloma presents with _____ bone lesions and hypercalcemia

Answer: lytic (punched-out)

Flashcard 65: PTLD has a variety of symptoms; ranging from symptoms that resemble _____ to malignancy induced dysfunction of the transplanted organ

Answer: mononucleosis

Flashcard 66: _____ is a mutated form of factor V that is resistant to degradation by activated protein C

Answer: Factor V Leiden

Flashcard 67: In pregnant women with APLA, management includes low-dose aspirin (_____ mg/day) and heparin (5,000 units SC twice daily); aspirin is typically stopped at 34 weeks.

Answer: 75-81

Extra: Aspirin is typically discontinued at 34–36 weeks' gestation to minimize bleeding risk during delivery and to prevent premature closure of the ductus arteriosus. Heparin is continued until delivery and resumed postpartum for 6 weeks. Note: 75 mg is the standard low-dose in the UK/India, while 81 mg is standard in the US.

Flashcard 68: The M spike seen in _____ is due to monoclonal IgM

Answer: Waldenstrom macroglobulinemia

Flashcard 69: _____ (vitamin A) is used to treat acute promyelocytic leukemia

Answer: All-trans-retinoic acid

Flashcard 70: Normocytic anemia with extravascular hemolysis is associated with _____ due to increased serum unconjugated bilirubin

Answer: jaundice