Blistering Diseases — Flashcards

Flashcard 11: Pemphigus foliaceus presents with _____ involvement

Answer: skin (only skin/both skin and mucosal)

Flashcard 12: Erythema multiforme _____ is characterised by mucous membrane involvement

Answer: major

Flashcard 13: Cicatricial pemphigoid involves the _____ layer of the basement membrane zone (BMZ)

Answer: Lamina lucida

Flashcard 14: Dermatitis herpetiformis and Linear IgA disease present with _____ rich infiltrate

Answer: neutrophil

Flashcard 15: Pemphigus vulgaris lesions heal _____ scarring.

Answer: Without

Flashcard 16: Epidermolysis bullosa _____ involves cleavage within the lamina lucida

Answer: junctionalis (junctional)

Extra: Levels of cleavage in Epidermolysis Bullosa (EB): • EB Simplex: Intraepidermal (basal cell layer) • Junctional EB: Lamina lucida • Dystrophic EB: Sub-lamina densa • EB Acquisita: Sub-lamina densa (autoimmune)

Flashcard 17: Degenerated acantholytic cells are seen on the Tzanck smear in SSSS, bullous impetigo, and pemphigus foliaceus at the level of stratum _____

Answer: Granulosum

Flashcard 18: Blistering skin lesions on sun-exposed skin (e.g., dorsum of hands) are characteristic of:

Answer: Porphyria cutanea tarda