Management of Autoimmune Bullous Diseases — Flashcards

Flashcard 1: _____ microabscesses are seen in Pemphigus vegetans

Answer: Eosinophilic

Flashcard 2: Cicatricial pemphigoid involves the _____ layer of the basement membrane zone (BMZ)

Answer: Lamina lucida

Flashcard 3: Direct immunofluoresence showing granular deposits at the tips of dermal papillae points to the diagnosis of _____

Answer: dermatitis herpetiformis

Flashcard 4: Epidermolysis bullosa _____ involves cleavage within the lamina lucida

Answer: junctionalis (junctional)

Extra: Levels of cleavage in Epidermolysis Bullosa (EB): • EB Simplex: Intraepidermal (basal cell layer) • Junctional EB: Lamina lucida • Dystrophic EB: Sub-lamina densa • EB Acquisita: Sub-lamina densa (autoimmune)

Flashcard 5: Epidermolysis bullosa _____ involves the stratum basale of the epidermis

Answer: simplex

Flashcard 6: Pemphigus vulgaris lesions heal _____ scarring.

Answer: Without

Flashcard 7: Pemphigus vulgaris is due to Ig_____ antibodies against desmoglein

Answer: G

Flashcard 8: Epidermolysis bullosa _____ is associated with mutations in the genes for K5/14

Answer: simplex

Flashcard 9: Tense _____, vesicles, and annular erythema are the characteristic triad of clinical features in Chronic Bullous Disorder of Childhood

Answer: Blisters