Question 1

Question

A 61-year-old man with a 45-pack-year smoking history presents with a 4-month history of progressive exertional dyspnea and a productive cough. He has no fever, hemoptysis, or weight loss. Spirometry is performed. Post-bronchodilator FEV1/FVC ratio is 0.58, and FEV1 is 52% of predicted. Lung volumes show a TLC of 128% predicted and RV of 185% predicted. Which of the following additional findings would most strongly support the underlying diagnosis over a restrictive pattern?

Accepted Answer

Increased residual volume with a concave expiratory limb on the flow-volume loop

Answer

Decreased DLCO with normal lung volumes on repeat plethysmography

Answer

Reduced TLC below 80% predicted with a preserved FEV1/FVC ratio above 0.70

Answer

Normal FEV1/FVC ratio that normalizes to above 0.70 after bronchodilator administration

Answer

Diffuse ground-glass opacities on high-resolution CT without air trapping

Cardiology — MCQs

Cardiology — MCQs

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