Inactivated whole virus vaccine

Inactivated whole virus vaccine. ***Inactivated whole virus vaccine*** - Covaxin is an **inactivated** vaccine, meaning it uses a **killed version of the SARS-CoV-2 virus** that cannot cause disease but can still stimulate an immune response. - This type of vaccine presents the **entire viral structure** to the immune system, leading to a broad immune response against various viral proteins. *Live attenuated vaccine* - A live attenuated vaccine uses a **weakened form of the virus** that can still replicate but does not cause severe disease. - While effective, live attenuated vaccines often carry a small risk of reversion to virulence, which is not the case for Covaxin. *Nucleic acid vaccine* - Nucleic acid vaccines (like mRNA or DNA vaccines) deliver **genetic material** (e.g., mRNA for the spike protein) into host cells to produce viral proteins, triggering an immune response. - Covaxin does not use genetic material directly for antigen production. *Protein subunit vaccine* - Protein subunit vaccines contain only specific, purified viral proteins (e.g., the spike protein) that are highly immunogenic. - Unlike subunit vaccines, Covaxin presents the immune system with the **entire inactivated virus**, not just isolated proteins. [Practice more Microbiology PYQs on OnCourse]

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UPSC-CMS 2021 — Microbiology

1 Previous Year Questions with Answers & Explanations

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All Subjects Anatomy (2)Anesthesiology (3)Community Medicine (32)Internal Medicine (8)Microbiology (1)Obstetrics and Gynecology (29)Pathology (3)Pediatrics (5)Pharmacology (2)Physiology (2)Radiology (1)Surgery (19)

Covaxin is a/an

UPSC-CMS 2021 Microbiology PYQs | 1+ Solved MCQs – Oncourse AI