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INI-CET 2018 — Anatomy

Q: In the given slide of cerebellum, the marked cell is inhibitory to?

Deep nuclei of cerebellum. ***Deep nuclei of cerebellum*** - The image shows a **Purkinje cell** (large, flask-shaped neuron with a prominent nucleolus, indicated by the arrow) located in the cerebellum. - Purkinje cells are the sole output neurons of the cerebellar cortex and exert an **inhibitory (GABAergic)** effect primarily on the **deep cerebellar nuclei.** *Vestibular nuclei* - While Purkinje cells of the **flocculonodular lobe and vermis** project to the vestibular nuclei, the primary and most direct inhibitory target discussed in the general context of Purkinje cell output are the deep cerebellar nuclei. - The Vestibular nuclei receive input from the cerebellum, but are not the sole or primary direct targets of all Purkinje cells. *Anterior horn of spinal cord* - The anterior horn of the spinal cord contains **motor neurons** and interneurons involved in motor control, but it does not receive direct innervation from Purkinje cells. - Cerebellar output influences spinal cord activity indirectly via relays in the brainstem and other motor control centers. *Basal ganglia* - The basal ganglia are subcortical nuclei involved in motor control and learning, forming a distinct neural circuit separate from the cerebellum. - There are **no direct inhibitory projections** from cerebellar Purkinje cells to the basal ganglia.

21 Questions — Page 3 of 3

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Q21

In the given slide of cerebellum, the marked cell is inhibitory to?