Renal Pathology — MCQs

A 32-year-old African-American male presents with recurrent edema of the feet and periorbital swelling. He has a history of high-risk sexual behavior. The blood pressure was 110/85 mm Hg. Results of laboratory investigations are as follows: HBs Ag: Negative, Blood glucose: Normal, HIV ELISA: Positive, 24-hour urine protein: 3.9 g, Urine microscopy: Fatty casts, oval fat bodies. An H and E stain of the renal biopsy is most likely to show what?

Crescentic glomerulonephritis with pauci-immune glomerulonephritis is associated with which of the following?

Haematuria is seen in all except:

Autosomal recessive kidney disease is caused due to mutation in which of the following genes?

Electron dense deposits in the region of hyalinosis and sclerosis with diffuse loss of foot processes seen in electron microscopy are features of which condition?

A 7-year-old boy presents with bilateral swelling around his eyes. His parents state that the child's eyes have become "puffy" over the past several weeks, and his urine has become cocoa-colored. Physical examination reveals bilateral periorbital edema, but peripheral edema is not found. The boy is afebrile and his blood pressure is slightly elevated. A urinary dipstick reveals mild proteinuria, while microscopic examination of the boy's urine reveals hematuria with red blood cell casts. Laboratory tests reveal increased ASO titers and decreased serum C3 levels, but C2 and C4 levels are normal. A throat swab for streptococci is negative. A microscopic section from the kidney reveals increased numbers of cells within the glomeruli. An electron microscopic section of the kidney reveals large electron-dense deposits in the glomeruli that are located between the basement membrane and the podocytes. The foot processes of the podocytes are otherwise unremarkable. Which one of the following renal diseases most likely produced the abnormalities in this young boy?

What is the most common type of renal lesion in children?

Which characteristic feature is seen in the kidney in malignant hypertension?

Visceral leishmaniasis is known to cause which type of glomerulonephritis?

Which disease is caused by anti-phospholipase A2 receptor antibody?