Pathogenesis of Viral Infections Practice Questions

Question 1

What is a potential outcome of the integration of a viral genome into a host cell chromosome?

Accepted Answer

All of the options

Answer

Altered growth

Answer

Malignancy

Answer

Latency

Question 2

Which of the following is not a component of innate immunity?

Accepted Answer

Helper T lymphocytes

Answer

Epithelial barriers

Answer

NK cells

Answer

Dendritic cells

Question 3

Assertion: VZV vaccine is live attenuated. Reason: It cannot be given to immunocompromised patients.

Accepted Answer

Both true, reason explains assertion

Answer

Both true, reason doesn't explain assertion

Answer

Assertion true, reason false

Answer

Assertion false, reason true

Question 4

Which of the following is an RNA oncogenic virus?

Accepted Answer

Human T-lymphotropic Virus (HTLV)

Answer

Cytomegalovirus (CMV)

Answer

Hepatitis B Virus (HBV)

Answer

Human Immunodeficiency Virus (HIV)

Question 5

All of the following are RNA viruses except

Accepted Answer

Herpes virus

Answer

Influenza virus

Answer

Parainfluenza virus

Answer

Mumps virus

Question 6

What is the mechanism behind the increased risk of HIV acquisition in individuals with genital herpes?

Accepted Answer

HSV disrupts epithelial barrier and recruits CD4+ cells

Answer

HSV glycoproteins enhance HIV binding to target cells

Answer

HSV inhibits local innate immune responses

Answer

HSV increases HIV viral load through transactivation

Question 7

Which of the following is true about anti-CMV IgG antibodies?

Accepted Answer

IgG avidity assay helps in differentiating past and primary infection

Answer

Denotes latent CMV infection

Answer

Denotes chronic CMV infection with immunity to other serotypes

Answer

Indicates acute CMV infection

Question 8

Histopathological feature of HIV encephalitis is/are-

Accepted Answer

Microglial nodules

Answer

Lewy body

Answer

Fibrillary plaque

Answer

Negri body

Question 9

Which of the following diseases is caused by the virus shown below?

Accepted Answer

Swimming pool conjunctivitis

Answer

Neurodegenerative disorder

Answer

Solid organ graft infection

Answer

Solid organ graft rejection

Question 10

Binding of gp120 causes:

Accepted Answer

Facilitation of co-receptor binding

Answer

Infection of target cell

Answer

Fusing of virus and target cell

Answer

None of the options

Pathogenesis of Viral Infections — MCQs

Pathogenesis of Viral Infections — MCQs

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