Automation in Microbiology Laboratory Practice Questions

Question 1

What is the best investigation for identifying malaria species?

Accepted Answer

Thin smear with Giemsa

Answer

Thick smear

Answer

QBC

Answer

Thin smear with acridine orange

Question 2

What is the mechanism of resistance in MRSA?

Accepted Answer

PBP2a alteration

Answer

Efflux pump activation

Answer

Porins modification

Answer

Beta-lactamase production

Question 3

All of the following are true about methicillin resistance in MRSA, except:

Accepted Answer

Resistance is primarily mediated/transmitted by plasmids

Answer

Resistance is produced as a result of altered PBPs

Answer

Resistance may be missed at incubation temperature of 37°C during susceptibility testing

Answer

Resistance is associated with increased minimum inhibitory concentrations (MICs) for beta-lactam antibiotics

Question 4

Which of the following is used to detect abnormal gene sequences EXCEPT?

Accepted Answer

Flow cytometry

Answer

RFLP analysis

Answer

Pyrosequencing

Answer

FISH

Question 5

The primary function of NIH (National Institutes of Health) is

Accepted Answer

Medical research

Answer

Public health policy

Answer

Clinical trials

Answer

Disease surveillance

Question 6

Test done for Mycobacterium tuberculosis based on CMI is

Accepted Answer

IGRA

Answer

GenXpert

Answer

BACTEC

Answer

Culture

Question 7

A patient presented with meningitis, and the CSF sample shows Gram-negative diplococci on Gram staining and microscopy. Which of the following features/tests will be characteristic of the organism?

Accepted Answer

Oxidase positive, catalase positive, ferments glucose and maltose

Answer

Catalase negative, optochin sensitive, alpha-hemolytic

Answer

Oxidase negative, catalase positive, coagulase positive

Answer

Catalase positive, urease positive, does not ferment glucose

Question 8

Which of the following organisms are acid-fast positive when decolorized with 20% sulfuric acid?

Accepted Answer

Mycobacterium tuberculosis

Answer

Mycobacterium avium

Answer

Mycobacterium leprae

Answer

Nocardia

Question 9

A young male patient presented with UTI. On urine examination, pus cells were found, but no organisms were visualized. Which method would be best for culture?

Accepted Answer

Mc Coy culture

Answer

Thayer Martin medium

Answer

Löwenstein-Jensen medium

Answer

Levinthal medium

Question 10

Phage typing is useful as an epidemiological tool in all of the following except?

Accepted Answer

Shigella dysenteriae

Answer

Salmonella

Answer

Staph aureus

Answer

V. cholerae

Automation in Microbiology Laboratory — MCQs

Automation in Microbiology Laboratory — MCQs

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