Multi-drug Resistant Tuberculosis Practice Questions

Question 1

Multi drug resistant tuberculosis is defined as resistance to?

Accepted Answer

INH and Rifampicin

Answer

Rifampicin and Pyrazinamide

Answer

Resistance to all first line drugs

Answer

INH and Pyrazinamide

Question 2

Which of the following is not included in the Revised National Tuberculosis Control Programme (RNTCP)?

Accepted Answer

Active case finding is a strategy used in tuberculosis control.

Answer

Chest X-rays are used as a diagnostic tool for tuberculosis.

Answer

Directly observed therapy (DOT) is a key strategy in tuberculosis control.

Answer

Daily drug administration is part of the tuberculosis treatment regimen.

Question 3

Which of the following is an inclusion criterion for the shorter bedaquiline regimen in the treatment of tuberculosis?

Accepted Answer

Rifampicin-resistant but fluoroquinolone-sensitive TB

Answer

Extrapulmonary TB like Tubercular meningitis

Answer

Rifampicin resistance with both KatG and inhA mutation

Answer

Rifampicin-sensitive TB

Answer

Extensively drug-resistant TB (XDR-TB)

Question 4

Which of the following is the true statement regarding measures to prevent typhoid transmission in the community?

Accepted Answer

Hygiene practice and clean sanitation control are more important than the typhoid vaccine.

Answer

Typhoid vaccine administration is the best method of preventing transmission.

Answer

Person-to-person transmission is the primary mode of spread.

Answer

Drug resistance in typhoid is not as big a problem as in TB.

Question 5

Not True about Bedaquiline

Accepted Answer

Contraindicated in pregnancy

Answer

Inhibits mycobacterial ATP synthase

Answer

Given in > 10 years aged patients

Answer

Given for MDR-TB patients

Question 6

A 50-year-old farmer presents with cough, fever, and weight loss. CXR shows upper lobe cavitary lesions. Sputum culture reveals acid-fast bacilli resistant to isoniazid and rifampin. What is the next best drug?

Accepted Answer

Fluoroquinolone

Answer

Linezolid

Answer

Ethambutol

Answer

Pyrazinamide

Question 7

Multidrug-resistant (MDR) tuberculosis shows resistance to which of the following drugs?

Accepted Answer

Isoniazid and rifampicin only

Answer

Isoniazid, rifampicin, and fluoroquinolone

Answer

Fluoroquinolone

Answer

Isoniazid, rifampicin, and kanamycin

Question 8

Which of the following methods is not suitable for testing anti-tubercular drug susceptibility?

Accepted Answer

Disc diffusion method

Answer

Resistance ratio method

Answer

Radiometric broth method

Answer

Molecular method

Question 9

Anti-tubercular drug susceptibility can be done by all of the following methods, except?

Accepted Answer

Disc diffusion method

Answer

Molecular method

Answer

Resistance ratio method

Answer

Radiometric broth method

Question 10

Multiple drug resistance is transferred through -

Accepted Answer

Conjugation

Answer

Transduction

Answer

Transformation

Answer

Mutation

Multi-drug Resistant Tuberculosis — MCQs

Multi-drug Resistant Tuberculosis — MCQs

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