Cardiology Practice Questions

Q: Which of these acyanotic congenital heart diseases is associated with volume overload?

Ventricular septal defect. ***Ventricular septal defect*** - A **ventricular septal defect (VSD)** causes a left-to-right shunt, leading to increased blood flow to the **pulmonary circulation** and the left side of the heart [1]. - This increased blood flow results in a **volume overload state** for the left atrium and left ventricle [1]. *Aortic stenosis* - **Aortic stenosis (AS)** is characterized by an obstruction to outflow from the left ventricle, leading to **pressure overload** on the left ventricle, not volume overload. - While prolonged AS can cause left ventricular hypertrophy, it doesn't primarily cause the type of volume overload seen with shunts. *None of the options* - This option is incorrect because **ventricular septal defect** is a specific acyanotic congenital heart disease that causes significant volume overload [1]. - **VSDs** are a classic example of conditions leading to increased pulmonary blood flow and chamber dilation due to shunting [1]. *Coarctation of aorta* - **Coarctation of the aorta** is a narrowing of the aorta, primarily causing **pressure overload** in the left ventricle due to increased resistance to systemic blood flow. - It does not cause a shunt or increased pulmonary blood flow, thus not leading to volume overload in the same way as VSD.

Q: Causes of wide fixed splitting of second heart sound include all except:

Ebstein anomaly. ***Ebstein anomaly*** - Ebstein anomaly is characterized by a **downward displacement of the tricuspid valve leaflets** into the right ventricle. - While it can cause wide splitting of S2 due to **right ventricular dysfunction** and prolonged RV ejection, the splitting is typically not fixed. *Right bundle branch block* - This condition causes a **delay in right ventricular depolarization**, leading to a prolonged right ventricular ejection time. - The delayed closure of the **pulmonary valve (P2)** relative to the aortic valve (A2) results in wide splitting of the second heart sound. *Total anomalous pulmonary venous return* - This condition involves all four **pulmonary veins connecting abnormally to the systemic venous circulation**. - It leads to an **obligate left-to-right shunt** at the atrial level, causing a chronic right ventricular volume overload and wide fixed splitting of S2 due to prolonged RV ejection time. *Atrial septal defect* - An **atrial septal defect (ASD)** results in a **left-to-right shunt**, increasing blood flow through the right ventricle and pulmonary artery [2]. - This increased flow prolongs **right ventricular ejection time**, leading to a physiologically fixed and wide splitting of the second heart sound [1][2].

Q: Neurocardiagenic syncope, the least useful investigation is -

Carotid duplex scan. ***Carotid duplex scan*** - This investigation evaluates for **carotid artery stenosis** and **atherosclerotic disease**, which is not relevant to neurocardiogenic syncope pathophysiology. - Neurocardiogenic syncope is a **reflex-mediated condition** involving inappropriate vasodilation and/or bradycardia, not mechanical vascular obstruction [2]. *Carotid sinus massage* - Relevant as a **provocative test** that can help identify reflex-mediated syncope by assessing **baroreflex sensitivity** [2]. - Can induce **bradycardia** or **hypotension** similar to neurocardiogenic syncope, making it diagnostically useful. *Echocardiography* - Essential for ruling out **structural heart disease** such as **valvular abnormalities**, **hypertrophic cardiomyopathy**, or **impaired ventricular function**. - Crucial in the **differential diagnosis** of syncope to distinguish cardiac causes from neurocardiogenic syncope [1]. *Orthostatic blood pressure recording* - While it may be normal in neurocardiogenic syncope, it remains a **fundamental, first-line investigation** in all syncope evaluations [3]. - Important to rule out **orthostatic hypotension** and should always be performed as part of basic syncope workup [1].

Q: Eisenmenger syndrome-True are All except ?

RV & LV walls come back to normal size. ***RV & LV walls come back to normal size*** - In **Eisenmenger syndrome**, there is **irreversible pulmonary hypertension** and **ventricular hypertrophy** due to chronic volume and pressure overload. - The right ventricle (RV) undergoes significant hypertrophy and dilatation to pump against increased pulmonary vascular resistance, and the left ventricle (LV) may also be affected due to the shift in the ventricular septum and changes in preload and afterload conditions. Therefore, these chambers **do not revert to normal size**. *Dilatation of central pulmonary artery* - This is a characteristic finding in **pulmonary hypertension**, which is a hallmark of Eisenmenger syndrome. - The central pulmonary arteries **dilate** due to the increased pressure, while more distal arteries constrict. *Peripheral pruning of pulmonary arteries* - In Eisenmenger syndrome, there is **progressive remodeling** of the pulmonary vasculature, leading to **narrowing and obliteration** of the smaller arteries. - This "pruning" effect means the distal pulmonary arteries become less visible on imaging. *Pulmonary veins are not distended* - **Eisenmenger syndrome** is primarily a condition of the **pulmonary arteries**, characterized by increased pressure and resistance. - The pulmonary veins which carry oxygenated blood to the left atrium, typically **do not become distended** as the primary issue is arterial and not a post-capillary or left-sided heart failure problem that would cause venous congestion.

Q: About carey coombs murmur which is false –

Can be associated with AR. *Carey Coombs murmur can be associated with AR* - The Carey Coombs murmur is caused by inflammation and thickening of the mitral valve in **acute rheumatic fever**, leading to increased flow velocity across the valve during diastole [3]. - It is **not directly associated with aortic regurgitation (AR)**; instead, AR can occur concurrently as part of the overall rheumatic heart disease aetiology, but the murmur itself is mitral in origin [1], [3]. *Mid-diastolic murmur* - The Carey Coombs murmur is indeed a **mid-diastolic murmur**, heard at the apex [2]. - This timing is due to the turbulent flow of blood across the inflamed **mitral valve** during the middle part of ventricular diastole [2]. *Seen in rheumatic fever* - The Carey Coombs murmur is a classic sign specifically associated with **acute rheumatic fever** [3]. - It results from inflammation of the mitral valve causing relative **mitral stenosis** and turbulence during diastole. *Low pitched murmur* - This murmur is typically described as **low-pitched and rumbling**, heard best with the bell of the stethoscope [2]. - Its low pitch is characteristic of turbulent flow caused by relative mitral stenosis [2].

Q: Which chamber of the heart is enlarged first in a patient with mitral stenosis?

Left atrium. ***Left atrium*** - **Mitral stenosis** obstructs blood flow from the left atrium to the left ventricle, leading to a build-up of pressure in the left atrium [1]. - This chronic pressure overload causes the **left atrium to dilate and hypertrophy** in an attempt to pump blood through the narrowed valve [1]. *Left ventricle* - In **mitral stenosis**, the left ventricle typically receives a reduced volume of blood, leading to a **smaller, underfilled left ventricle**, rather than enlargement. - Its workload is decreased due to reduced preload, so it does not hypertrophy or dilate primarily. *Right ventricle* - **Right ventricular enlargement** can eventually occur in severe and chronic mitral stenosis due to **pulmonary hypertension** caused by back pressure from the left atrium, but it is not the *first* chamber to be affected [1], [2]. - Increased pressure in the pulmonary circulation increases the workload on the right ventricle, leading to hypertrophy and dilation over time [1], [2]. *Right atrium* - **Right atrial enlargement** is a consequence of chronic and severe pulmonary hypertension affecting the right ventricle, which then causes back pressure into the right atrium [1]. - This is a very late manifestation of mitral stenosis, occurring after significant involvement of the left atrium and pulmonary vasculature.

Q: Which is not seen in heart failure?

Oligemia. ***Oligemia*** - **Oligemia** refers to a reduced blood volume or total blood flow to a region, which is typically not observed in **heart failure**. - In **heart failure**, the body often experiences **fluid overload** and **pulmonary congestion**, leading to increased blood volume in the lungs, not reduced [1]. *Cardiomegaly* - **Cardiomegaly**, or an enlarged heart, is a common finding in **heart failure** as the heart muscle remodels and dilates to compensate for impaired pumping function [1], [3]. - This can be seen on a chest X-ray as an **increased cardiothoracic ratio** [1], [2]. *Kerley B lines* - **Kerley B lines** are thin, horizontal lines visible on a chest X-ray, typically found at the lung periphery. - They indicate **interstitial edema** due to increased pulmonary venous pressure, a characteristic sign of **pulmonary congestion** in **heart failure** [1]. *Kerley A Lines* - **Kerley A lines** are longer, less common lines seen radiating from the hila towards the upper lobes. - These lines represent **distended anastomotic channels** between pulmonary and systemic venous systems, also indicative of **pulmonary edema** and **heart failure** [1], [4].

Q: A person was brought to emergency department and was diagnosed with Supra ventricular tachycardia and suddenly he became unstable. What is the next line of management?

DC Cardioversion. ***DC Cardioversion*** - For **unstable supraventricular tachycardia (SVT)**, immediate **direct current (DC) cardioversion** is the definitive treatment to restore sinus rhythm. - Instability in SVT includes symptoms like hypotension, altered mental status, signs of shock, ischemic chest discomfort, or acute heart failure. *Intravenous ibutilide* - **Ibutilide** is an antiarrhythmic drug used for pharmacological cardioversion of recent-onset atrial fibrillation or flutter, but not typically for unstable SVT. - While it can convert certain supraventricular arrhythmias, it is generally reserved for **stable patients** and takes longer to act than immediate electrical cardioversion. *Intravenous Diltiazem* - **Diltiazem** is a calcium channel blocker used to control ventricular rate in **stable SVT**, atrial fibrillation, or flutter [1]. - It is contraindicated in unstable patients as it can further depress cardiac contractility and worsen hypotension [2]. *Intravenous Flecainide* - **Flecainide** is a class Ic antiarrhythmic drug used to maintain sinus rhythm in patients with supraventricular arrhythmias, including SVT. - It also takes time to act and is used in **stable patients** without structural heart disease, not in emergency unstable situations where immediate rhythm conversion is required.

Q: Which disease does not cause AV nodal block?

Cat scratch. ### Cat scratch - While cat scratch disease (caused by *Bartonella henselae*) can cause **lymphadenopathy** and other systemic symptoms, it is not typically associated with **AV nodal block** or direct cardiac involvement [1]. - The disease is usually self-limiting and rarely affects the electrical conduction system of the heart. ### Toxoplasmosis - **Toxoplasmosis**, caused by *Toxoplasma gondii*, can lead to **myocarditis** and **pericarditis**, which may disrupt the heart's electrical activity and cause AV nodal blocks, especially in immunocompromised individuals. - The parasite can directly infect cardiac muscle cells, leading to inflammation and conduction abnormalities. ### Chagas - **Chagas disease**, caused by *Trypanosoma cruzi*, is well-known for its propensity to cause **chronic Chagasic cardiomyopathy**, which frequently includes **AV nodal block** and other conduction defects [2]. - The parasite directly invades cardiac tissue, leading to fibrosis and destruction of the conduction system [2]. ### Lyme disease - **Lyme carditis**, a manifestation of Lyme disease caused by *Borrelia burgdorferi*, is a common cause of **AV nodal block**, often presenting with varying degrees of block. - The spirochete can directly infect the heart muscle, leading to inflammation and disruption of electrical pathways.

Question 1

Which of these acyanotic congenital heart diseases is associated with volume overload?

Accepted Answer

Ventricular septal defect

Answer

Aortic stenosis

Answer

None of the options

Answer

Coarctation of aorta

Question 2

Which of the following statements is false about ostium secundum ASD?

Accepted Answer

Narrow splitting of the second heart sound is a feature of ostium secundum ASD.

Answer

A prominent shunt murmur is often heard in ostium secundum ASD.

Answer

Fixed splitting of the second heart sound is a feature of ostium secundum ASD.

Answer

Left axis deviation in ECG is commonly seen in ostium secundum ASD.

Answer

Right axis deviation in ECG is commonly seen in ostium secundum ASD.

Question 3

Causes of wide fixed splitting of second heart sound include all except:

Accepted Answer

Ebstein anomaly

Answer

Right bundle branch block

Answer

Total anomalous pulmonary venous return

Answer

Atrial septal defect

Question 4

Neurocardiagenic syncope, the least useful investigation is -

Accepted Answer

Carotid duplex scan

Answer

Carotid sinus massage

Answer

Echocardiography

Answer

Orthostatic blood pressure recording

Question 5

Eisenmenger syndrome-True are All except ?

Accepted Answer

RV & LV walls come back to normal size

Answer

Dilatation of central pulmonary artery

Answer

Peripheral pruning of pulmonary arteries

Answer

Pulmonary veins are not distended

Question 6

About carey coombs murmur which is false –

Accepted Answer

Can be associated with AR

Answer

Mid-diastolic murmur

Answer

Seen in rheumatic fever

Answer

Low pitched murmur

Question 7

Which chamber of the heart is enlarged first in a patient with mitral stenosis?

Accepted Answer

Left atrium

Answer

Left ventricle

Answer

Right ventricle

Answer

Right atrium

Question 8

Which is not seen in heart failure?

Accepted Answer

Oligemia

Answer

Cardiomegaly

Answer

Kerley B lines

Answer

Kerley A Lines

Question 9

A person was brought to emergency department and was diagnosed with Supra ventricular tachycardia and suddenly he became unstable. What is the next line of management?

Accepted Answer

DC Cardioversion

Answer

Intravenous ibutilide

Answer

Intravenous Diltiazem

Answer

Intravenous Flecainide

Question 10

Which disease does not cause AV nodal block?

Accepted Answer

Cat scratch

Answer

Toxoplasmosis

Answer

Chagas

Answer

Lyme disease

Cardiology — MCQs

Cardiology — MCQs

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