Diseases of the Nose and Paranasal Sinuses — MCQs

A 55-year-old male presents with left-sided maxillary tooth pain. Dental examination reveals no abnormalities of his teeth. Physical examination shows that tapping on his right maxilla elicits sharp pain on the right side of his face. The patient reports no allergies. Which of the following conditions is the most likely diagnosis?

Q159Medium

Which of the following is not a feature of rhinosporidiosis?

Q160Medium

A 39-year-old woman presents with a 6-month history of headache, facial pressure, nasal obstruction with discharge, and diminished taste sensation. Physical examination reveals discomfort on palpation over her left maxillary sinus. Rhinoscopy shows nasal erythema, marked edema, and purulent discharge. Which of the following complications is most likely to occur in this patient?

Diseases of the Nose and Paranasal Sinuses Indian Medical PG Practice Questions and MCQs

Question 151: Miriam, a college student with acute rhinitis, sees the campus nurse because of excessive nasal drainage. The nurse asks the patient about the color of the drainage. In acute rhinitis, nasal drainage is normally:

A. Yellow
B. Green
C. Clear (Correct Answer)
D. Gray

Explanation: **Explanation:** **1. Why "Clear" is Correct:** Acute rhinitis, most commonly caused by viral infections (like the common cold/Rhinovirus), typically presents with a **clear, watery nasal discharge** (rhinorrhea) in its initial stages. This is due to the hypersecretion of mucus glands and increased capillary permeability in the nasal mucosa as an inflammatory response to the virus. In the absence of secondary bacterial infection, the discharge remains serous or mucoid. **2. Why Other Options are Incorrect:** * **Yellow (A) and Green (B):** These colors typically indicate the presence of **purulent** discharge. The color change is caused by the release of the enzyme myeloperoxidase from disintegrating neutrophils. While viral rhinitis can sometimes turn yellowish as it resolves, persistent yellow or green discharge is more characteristic of **acute bacterial rhinosinusitis**. * **Gray (D):** Grayish or "dirty" membranes/discharge are not typical of simple acute rhinitis. This color is more associated with specific pathologies like **Diphtheritic rhinitis** (grayish-white pseudomembrane) or certain fungal infections (e.g., Mucormycosis, which may show black/gray eschar). **3. NEET-PG High-Yield Pearls:** * **Stages of Acute Rhinitis (Coryza):** 1. *Ischemic stage:* Burning sensation in the nose. 2. *Hyperemic stage:* Profuse watery discharge and sneezing. 3. *Stage of secondary infection:* Discharge becomes mucopurulent (yellow/green). 4. *Resolution.* * **Differential Diagnosis:** If the discharge is clear but associated with paroxysmal sneezing and itchy eyes, consider **Allergic Rhinitis** (look for "pale/bluish mucosa" and "eosinophils on smear"). * **Unilateral clear discharge:** Always rule out **CSF Rhinorrhea** (test for Beta-2 transferrin or Glucose levels).

Question 152: Which X-ray view is primarily used for assessing a nasal fracture?

A. Waters view
B. Caldwell's view
C. Lateral view (Correct Answer)
D. Occlusal anterior view

Explanation: **Explanation:** **1. Why the Lateral View is Correct:** The **Lateral view of the nasal bones** is the most sensitive and specific radiographic projection for diagnosing nasal fractures. Since the nasal bones are thin, midline structures, a lateral projection allows for the visualization of cortical disruptions, depressions, or displacements of the nasal bridge without the overlap of denser facial bones (like the maxilla or zygoma). It is particularly useful for identifying transverse fractures and assessing the degree of posterior displacement. **2. Why the Other Options are Incorrect:** * **Waters View (Occipitomental):** This is the gold standard for visualizing the **maxillary sinuses**. While it can show the orbital rim and zygomatic arch, the nasal bones are foreshortened and poorly visualized. * **Caldwell’s View (Occipitofrontal):** This is primarily used for the **frontal and ethmoid sinuses**. The nasal bones are obscured by the shadow of the frontal bone and the base of the skull. * **Occlusal Anterior View:** This is a dental radiograph used to visualize the floor of the mouth or the palate. It is not used for assessing the nasal dorsum. **3. Clinical Pearls for NEET-PG:** * **Clinical Diagnosis:** Remember that a nasal fracture is primarily a **clinical diagnosis** (based on epistaxis, deformity, and crepitus). X-rays are often unnecessary for management but are frequently done for medico-legal purposes. * **Best Imaging:** If a complex midfacial fracture is suspected (e.g., Le Fort fractures), a **Non-Contrast CT (NCCT) of the Paranasal Sinuses** is the investigation of choice. * **Waters View Tip:** It is the best view for the **Maxillary sinus** and to see the **orbital floor** (Blow-out fractures).

Question 153: In Caldwell-Luc operation, the nasoantral window is made through which anatomical structure?

A. Superior meatus
B. Inferior meatus (Correct Answer)
C. Middle meatus
D. None of the above

Explanation: ### Explanation The **Caldwell-Luc operation** is a surgical procedure where the maxillary sinus is accessed via the canine fossa (sublabial approach). A key step in this surgery is the creation of a **nasoantral window** to ensure permanent dependent drainage and ventilation of the sinus. **Why Option B is Correct:** The nasoantral window is created in the **inferior meatus**. This site is chosen because the bone in the lateral wall of the inferior meatus is thin, and it provides the most **dependent (lowest) point** for gravity-assisted drainage of secretions from the maxillary sinus into the nasal cavity. **Why Other Options are Incorrect:** * **Option A (Superior Meatus):** This area is located high in the nasal cavity and contains the openings for the posterior ethmoidal cells. It is anatomically distant from the maxillary sinus floor. * **Option C (Middle Meatus):** While the natural ostium of the maxillary sinus is located in the middle meatus (hiatus semilunaris), this is the site for **Functional Endoscopic Sinus Surgery (FESS)**, not the nasoantral window of a Caldwell-Luc procedure. **High-Yield Clinical Pearls for NEET-PG:** * **Indications for Caldwell-Luc:** Recurrent antrochoanal polyps, removal of foreign bodies/root of a tooth from the sinus, orbital floor decompression, and management of maxillary fractures. * **Incision:** Sublabial incision is made above the premolar teeth (avoiding the midline to preserve the nerve supply). * **Complication:** The most common complication is **cheek swelling and numbness** due to injury to the **infraorbital nerve**. * **Trend Shift:** FESS has largely replaced Caldwell-Luc for chronic sinusitis, as FESS preserves the mucociliary clearance mechanism toward the natural ostium.

Question 154: To prevent synechiae formation after nasal surgery, which one of the following is the most useful packing?

A. Mitomycin (Correct Answer)
B. Ribbon gauze
C. Ribbon gauze with liquid paraffin
D. Ribbon gauze with steroids

Explanation: **Explanation:** **1. Why Mitomycin C is the correct answer:** Mitomycin C (MMC) is a potent **alkylating agent** derived from *Streptomyces caespitosus*. Its primary mechanism involves inhibiting **fibroblast proliferation** and collagen synthesis. In the context of nasal surgery (like FESS or septoplasty), synechiae (adhesions) occur due to the healing of two opposing denuded mucosal surfaces. Topical application of Mitomycin C (usually 0.4 mg/ml) significantly reduces the formation of granulation tissue and scarring, making it the most effective pharmacological agent to prevent post-operative synechiae. **2. Why the other options are incorrect:** * **Ribbon gauze (B):** Plain gauze is abrasive and can cause mucosal trauma upon removal, which may actually trigger inflammatory responses and promote adhesion formation. * **Ribbon gauze with liquid paraffin (C):** While paraffin reduces trauma during removal by providing lubrication, it does not possess any intrinsic anti-fibrotic properties to prevent the biological process of synechiae formation. * **Ribbon gauze with steroids (D):** While steroids have anti-inflammatory properties and are used to prevent polyp recurrence, they are generally considered less potent than Mitomycin C in specifically inhibiting the fibroblast activity required to prevent dense adhesions. **Clinical Pearls for NEET-PG:** * **Other uses of Mitomycin C in ENT:** It is also used to maintain patency in **choanal atresia surgery**, subglottic stenosis repair, and dacryocystorhinostomy (DCR). * **Most common site for synechiae:** Between the **middle turbinate** and the lateral nasal wall (often leading to ostiomeatal complex obstruction). * **Prevention:** Apart from MMC, the use of **Silastic splints** or non-absorbable spacers (like Merocel) are common mechanical methods to prevent adhesions.

Question 155: Ringertz tumor is seen commonly in which anatomical location?

A. Nose and sinuses (Correct Answer)
B. Stomach
C. Upper part of neck
D. Mediastinum

Explanation: **Explanation:** **Ringertz tumor** is the eponym for **Inverted Papilloma** (Schneiderian papilloma). It is a benign but locally aggressive epithelial tumor that arises from the Schneiderian membrane, which lines the nasal cavity and paranasal sinuses. 1. **Why Option A is Correct:** The tumor typically originates from the **lateral wall of the nose** (most commonly the middle meatus or ethmoid sinus). Its hallmark feature is the endofytic (inward) growth of surface epithelium into the underlying stroma, rather than outward growth. This unique histological pattern is why it is called "inverted." 2. **Why Other Options are Incorrect:** * **Option B (Stomach):** While the GI tract can have various papillomas or adenomas, the Ringertz tumor is specific to the respiratory mucosa of the sinonasal tract. * **Option C (Neck):** Masses in the upper neck are usually lymph nodes, branchial cysts, or carotid body tumors, not Schneiderian papillomas. * **Option D (Mediastinum):** Mediastinal masses are typically thymomas, lymphomas, or germ cell tumors. **High-Yield Clinical Pearls for NEET-PG:** * **Site of Origin:** Lateral wall of the nose (most common) > Maxillary sinus > Ethmoid sinus. * **Clinical Presentation:** Unilateral nasal obstruction and epistaxis. * **Malignant Potential:** It is associated with **Squamous Cell Carcinoma** in about 5–15% of cases. * **Management:** Requires wide surgical excision (usually via Medial Maxillectomy or Endoscopic Sinus Surgery) because it has a **high recurrence rate** if incompletely removed. * **Radiology:** Often shows a "bony remodeling" or "focal hyperostosis" at the site of origin on a CT scan.

Question 156: Which is the largest turbinate in the nose?

A. Superior
B. Middle
C. Inferior (Correct Answer)
D. All are the same size

Explanation: **Explanation:** The nasal turbinates (conchae) are bony projections from the lateral wall of the nose covered by respiratory mucosa. Among the three, the **Inferior Turbinate** is the largest. **Why the Inferior Turbinate is the correct answer:** The inferior turbinate is a **separate bone** (unlike the superior and middle turbinates, which are parts of the ethmoid bone). It runs almost the entire length of the nasal cavity floor. It is highly vascular, containing cavernous venous sinusoids that play a crucial role in the "nasal cycle" by regulating airflow and humidification through periodic swelling and shrinking. **Analysis of Incorrect Options:** * **A. Superior Turbinate:** This is the smallest of the three turbinates. It is located high in the nasal vault and protects the olfactory epithelium. * **B. Middle Turbinate:** This is an intermediate-sized structure. It is a key landmark in endoscopic sinus surgery (FESS) as it overlies the osteomeatal complex. * **D. All are the same size:** This is anatomically incorrect; the turbinates follow a size hierarchy (Inferior > Middle > Superior). **Clinical Pearls for NEET-PG:** * **Embryology:** The inferior turbinate develops from the maxilloturbinal, while the superior and middle turbinates develop from the ethmoturbinals. * **Nasolacrimal Duct:** The inferior meatus (located below the inferior turbinate) is the site where the nasolacrimal duct drains. * **Hypertrophy:** Chronic allergic rhinitis often leads to "mulberry" hypertrophy of the inferior turbinate, which may require surgical reduction (turbinoplasty). * **Agger Nasi:** This is the most anterior ethmoidal air cell, located just anterior to the attachment of the middle turbinate.

Question 157: A child presents with a history of unilateral purulent nasal discharge with occasional bloody discharge from the same side. What is the most likely diagnosis?

A. Antrochoanal polyp
B. Foreign body (Correct Answer)
C. Angiofibroma
D. Rhinosporidiosis

Explanation: ### Explanation The clinical presentation of **unilateral, foul-smelling, purulent nasal discharge** in a child is considered a **foreign body (FB) in the nose** until proven otherwise. **Why Foreign Body is Correct:** When a child inserts an inanimate object into the nasal cavity, it causes local irritation, mucosal ulceration, and secondary bacterial infection. This leads to the classic triad of symptoms: unilateral discharge, fetid odor (due to saprophytic infection), and occasional blood-staining (due to granulation tissue formation). **Analysis of Incorrect Options:** * **Antrochoanal Polyp:** While it presents with unilateral nasal obstruction, the discharge is typically mucoid and not foul-smelling or bloody. It is more common in older children and adolescents. * **Angiofibroma:** This is a benign but aggressive tumor seen almost exclusively in **adolescent males**. It presents with profuse, spontaneous epistaxis and nasal obstruction, rather than chronic purulent discharge. * **Rhinosporidiosis:** Caused by *Rhinosporidium seeberi*, it presents as a leafy, friable, strawberry-like vascular mass. While it can cause bleeding, it is usually associated with a history of bathing in stagnant water and presents with a visible mass rather than just discharge. **Clinical Pearls for NEET-PG:** * **Gold Standard Diagnosis:** Anterior rhinoscopy or diagnostic nasal endoscopy. * **Management:** Removal using a Hook (e.g., Eustachian cushion or Jobson Horne probe). **Never use forceps** for smooth/round foreign bodies, as they may slip and be aspirated into the airway. * **Rhinolith:** A long-standing neglected foreign body can act as a nucleus for calcium and magnesium salt deposition, forming a "nasal stone." * **Button Battery:** This is a **surgical emergency** due to the risk of liquefactive necrosis and septal perforation within hours.

Question 158: A 55-year-old male presents with left-sided maxillary tooth pain. Dental examination reveals no abnormalities of his teeth. Physical examination shows that tapping on his right maxilla elicits sharp pain on the right side of his face. The patient reports no allergies. Which of the following conditions is the most likely diagnosis?

A. Sphenoid sinusitis
B. Anterior ethmoidal sinusitis
C. Posterior ethmoidal sinusitis
D. Maxillary sinusitis (Correct Answer)

Explanation: **Explanation:** The patient presents with classic symptoms of **Acute Maxillary Sinusitis**. The maxillary sinus is the largest of the paranasal sinuses and is located in the body of the maxilla. **1. Why Maxillary Sinusitis is correct:** * **Referred Pain:** The roots of the upper premolar and molar teeth are in close proximity to the floor of the maxillary sinus (separated only by a thin layer of bone or mucous membrane). Both the sinus lining and the teeth are supplied by the **Superior Alveolar nerves** (branches of the Maxillary nerve, V2). Therefore, inflammation in the sinus is frequently perceived as dental pain (referred pain). * **Tenderness:** Tapping over the canine fossa (the thinnest part of the anterior maxillary wall) elicits sharp pain, which is a hallmark clinical sign of maxillary involvement. **2. Why other options are incorrect:** * **Sphenoid Sinusitis:** Typically presents with pain referred to the **vertex** (top of the head), occiput, or behind the eyes. It does not cause dental or cheek tenderness. * **Ethmoidal Sinusitis:** * **Anterior Ethmoidal:** Pain is usually localized to the **bridge of the nose**, the inner canthus, or the medial orbit. * **Posterior Ethmoidal:** Pain is often referred to the **mastoid area** or the vertex. **Clinical Pearls for NEET-PG:** * **Most common sinus involved** in adults is the Maxillary sinus; in children, it is the Ethmoid sinus. * **First-line investigation:** X-ray Water’s view (Occipitomental view) shows haziness or an air-fluid level. * **Gold Standard investigation:** Non-Contrast CT (NCCT) of the Paranasal Sinuses. * **Drainage:** The maxillary sinus drains into the **middle meatus** via the hiatus semilunaris. Its drainage is unique because the ostium is located superiorly, requiring ciliary action to move mucus against gravity.

Question 159: Which of the following is not a feature of rhinosporidiosis?

A. Oral dapsone is useful in treatment
B. Excision with the knife is the treatment
C. Bleeding polyp
D. Russell bodies are seen (Correct Answer)

Explanation: **Explanation:** Rhinosporidiosis is a chronic granulomatous infection caused by *Rhinosporidium seeberi* (now classified as a Mesomycetozoan parasite). It primarily affects the nasal mucosa, presenting as a leafy, friable, strawberry-like vascular mass. **Why "Russell bodies are seen" is the correct (incorrect feature) answer:** Russell bodies are eosinophilic, large immunoglobulin-containing inclusions found in plasma cells, typically associated with chronic inflammation (e.g., Rhinoscleroma). They are **not** a feature of Rhinosporidiosis. The characteristic histopathological hallmark of Rhinosporidiosis is the presence of numerous **sporangia** in various stages of development, containing thousands of **endospores**. **Analysis of other options:** * **Option A (Oral dapsone):** Dapsone is used as an adjunct to surgery. It inhibits the maturation of sporangia and arrests the growth of the organism, thereby reducing the high recurrence rate. * **Option B (Excision with knife):** Wide surgical excision is the primary treatment. However, it must be performed with **cauterization of the base** (using diathermy) to prevent seeding of endospores and recurrence. * **Option C (Bleeding polyp):** Due to its extreme vascularity, the lesion is often referred to as a "bleeding polyp of the nose." Epistaxis is a common presenting symptom. **High-Yield Clinical Pearls for NEET-PG:** * **Epidemiology:** Most common in South India (Tamil Nadu, Kerala) and Sri Lanka; associated with bathing in stagnant pond water. * **Pathology:** Look for "Strawberry appearance" (white dots on a red mass representing mature sporangia). * **Staining:** Sporangia stain well with GMS, PAS, and Mucicarmine. * **Key Distinction:** Rhinoscleroma = Mikulicz cells & Russell bodies; Rhinosporidiosis = Sporangia & Endospores.

Question 160: A 39-year-old woman presents with a 6-month history of headache, facial pressure, nasal obstruction with discharge, and diminished taste sensation. Physical examination reveals discomfort on palpation over her left maxillary sinus. Rhinoscopy shows nasal erythema, marked edema, and purulent discharge. Which of the following complications is most likely to occur in this patient?

A. Mucocele
B. Nasopharyngeal carcinoma
C. Osteomyelitis (Correct Answer)
D. Sinonasal papilloma

Explanation: ### Explanation The patient presents with classic symptoms of **Chronic Rhinosinusitis (CRS)**: headache, facial pressure, purulent discharge, and hyposmia (diminished taste/smell) lasting more than 12 weeks. The physical findings of erythema, edema, and tenderness over the maxillary sinus confirm an ongoing inflammatory/infectious process. **1. Why Osteomyelitis is the Correct Answer:** Osteomyelitis is a recognized, serious complication of untreated or inadequately treated suppurative sinusitis. It occurs through **retrograde thrombophlebitis** of the valveless diploic veins or by direct extension of the infection to the bone. In the context of the maxillary sinus, it can lead to sequestration of the maxilla. While orbital and intracranial complications are more common in frontal/ethmoid sinusitis, osteomyelitis remains a high-yield systemic complication of chronic sinus infections in NEET-PG scenarios. **2. Why the Other Options are Incorrect:** * **Mucocele (A):** While a mucocele is a complication of chronic sinusitis (due to duct obstruction), it is a chronic, cystic expansion rather than an acute infectious spread. Given the "purulent discharge" and "marked edema," the question emphasizes an active, aggressive infection. * **Nasopharyngeal Carcinoma (B):** This is a malignancy associated with EBV and genetics; it is not a complication of rhinosinusitis. * **Sinonasal Papilloma (D):** These are benign epithelial tumors (e.g., Inverted Papilloma) related to HPV or chronic irritation, but they are not direct complications of an infectious process. **Clinical Pearls for NEET-PG:** * **Pott’s Puffy Tumor:** A specific type of osteomyelitis of the frontal bone presenting as a doughy swelling on the forehead; it is a classic complication of frontal sinusitis. * **Most common complication of Sinusitis:** Orbital complications (specifically Preseptal/Orbital Cellulitis), usually arising from the ethmoid sinus via the *lamina papyracea*. * **Diagnosis:** Contrast-enhanced CT (CECT) is the gold standard for evaluating complications of sinusitis.

Practice by Chapter

Rhinitis

Practice Questions

Acute Rhinosinusitis

Practice Questions

Chronic Rhinosinusitis

Practice Questions

Nasal Polyposis

Practice Questions

Allergic Fungal Sinusitis

Practice Questions

Deviated Nasal Septum

Practice Questions

Epistaxis

Practice Questions

Nasal Trauma

Practice Questions

Choanal Atresia

Practice Questions

CSF Rhinorrhea

Practice Questions

Tumors of the Nose and Paranasal Sinuses

Practice Questions

Complications of Sinusitis

Practice Questions

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