Membrane Receptors and Signal Transduction Practice Questions

Question 1

JAK-STAT kinase receptors are associated with?

Accepted Answer

Nuclear transcription

Answer

Ion channels

Answer

IP3 - DAG

Answer

cAMP

Question 2

A partial agonist has:

Accepted Answer

High affinity with low intrinsic activity

Answer

High affinity with no intrinsic activity

Answer

Low affinity with high intrinsic activity

Answer

Low affinity with low intrinsic activity

Question 3

Which of the following act through tyrosine kinase receptor:

Accepted Answer

Insulin

Answer

GH

Answer

FSH

Answer

Glucagon

Question 4

Which of the following statements best describes the mechanism of action of insulin on target cells?

Accepted Answer

Insulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

Answer

Insulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

Answer

Insulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

Answer

Insulin enters the cell and causes the release of calcium ions from intracellular stores.

Question 5

Which of the following hormones uses cGMP as a second messenger?

Accepted Answer

Atrial natriuretic peptide (ANP)

Answer

Insulin

Answer

Thyroxine

Answer

Growth hormone

Question 6

Which of the following act through G protein coupled receptors?

Accepted Answer

Ach Muscarinic receptors

Answer

Insulin receptors

Answer

Ach Nicotinic receptors

Answer

GABA-A receptors

Question 7

A primigravida at 38 weeks of gestation has gone into labor. Oxytocin was started to augment labor. The second messenger system through which oxytocin acts is:

Accepted Answer

Phospholipase C (IP3/DAG pathway)

Answer

Tyrosine kinase

Answer

cGMP

Answer

cAMP

Question 8

Proteoglycan present in the glomerular basement membrane is?

Accepted Answer

Heparan sulfate

Answer

Keratan sulfate 1

Answer

Keratan sulfate 2

Answer

Chondroitin sulfate

Question 9

Which of the following binds to Tyrosine Kinase receptor?

Accepted Answer

Insulin

Answer

Glucagon

Answer

Prolactin

Answer

Growth Hormone

Question 10

Maximum fluidity of the cell membrane is due to?

Accepted Answer

arachidonic acid

Answer

palmitic acid

Answer

alpha-linolenic acid

Answer

linoleic acid (18:2)

Membrane Receptors and Signal Transduction — MCQs

Membrane Receptors and Signal Transduction — MCQs

Want unlimited practice?