Preoperative Evaluation of Pediatric Patients — MCQs
Which of the following is the induction anesthesia of choice in the pediatric age group?
A 6-year-old child is scheduled for tonsillectomy. Which inhalational agent is most suitable for induction?
In a 2 months old infant undergoing surgery for biliary atresia, you would avoid one of the following anaesthetic -
A 50 year old male is posted for elective laparoscopic cholecystectomy. No history of comorbidities. His surgery is scheduled at 2 PM on the day of surgery. Which of the following is against the ASA guidelines for preoperative fasting
Which of the following is the necessary pre-operative investigation which has to be done in a patient with Down's syndrome posted for surgery?
According to the DSM-5 criteria for Autism Spectrum Disorder, which of the following is required for diagnosis in children?
An unconscious child is brought to the casualty. What is the correct sequence of the management?
A one-year-old child, preterm, and low birth weight with delayed milestones is posted for elective hernia repair. Which of the following statements is true?
Modified Mallampati grading is used in assessment of -
Juvenile polyp is a type of which of the following?
Preoperative Evaluation of Pediatric Patients Indian Medical PG Practice Questions and MCQs
Question 1: Which of the following is the induction anesthesia of choice in the pediatric age group?
- A. A. Sevoflurane (Correct Answer)
- B. B. Desflurane
- C. C. Halothane
- D. D. Isoflurane
Explanation: ***A. Sevoflurane*** - **Sevoflurane** is an inhalation anesthetic widely preferred for **pediatric induction** due to its rapid onset and non-pungent odor, which makes it well-tolerated by children. - Its low blood-gas partition coefficient allows for swift changes in anesthetic depth and rapid emergence. *B. Desflurane* - **Desflurane** has a **pungent odor** and is known to cause airway irritation, making it unsuitable for inhalational induction in children. - Its rapid onset and offset are beneficial, but its irritant properties limit its use for induction, especially in younger patients. *C. Halothane* - **Halothane** was previously used for pediatric induction but has largely been replaced due to its association with **hepatotoxicity** and cardiac arrhythmias. - It also has a slower onset and offset compared to newer agents like sevoflurane. *D. Isoflurane* - **Isoflurane** has a **pungent odor** and can cause airway irritation, making it less suitable for inhalational induction in children compared to sevoflurane. - While effective for maintenance, its irritant properties make for a less smooth and potentially distressing induction experience for pediatric patients.
Question 2: A 6-year-old child is scheduled for tonsillectomy. Which inhalational agent is most suitable for induction?
- A. Isoflurane
- B. Halothane
- C. Sevoflurane (Correct Answer)
- D. Desflurane
Explanation: ***Sevoflurane*** - **Sevoflurane** is preferred for inhalational induction in pediatric patients due to its **low pungency** and rapid onset/offset, making it well-tolerated and less likely to cause coughing or breath-holding. - Its **minimal airway irritancy** facilitates a smooth induction, which is particularly important in children who may be uncooperative or anxious. *Isoflurane* - **Isoflurane** is a **pungent** inhalational agent, making it unsuitable for inhalational induction, especially in children, as it can cause coughing, breath-holding, and laryngospasm. - While it has a good safety profile for maintenance, its irritant properties preclude its use for a smooth mask induction. *Halothane* - **Halothane** was previously a common pediatric anesthetic but is rarely used now due to its association with **hepatotoxicity** (halothane hepatitis) and increased risk of **cardiac arrhythmias**. - Although it has a pleasant odor, its significant side effect profile has led to its replacement by safer agents like sevoflurane. *Desflurane* - **Desflurane** is very **pungent** and highly irritating to the airway, causing coughing, breath-holding, and laryngospasm, making it unsuitable for inhalational induction, especially in pediatric patients. - It also has a **high MAC value**, requiring higher concentrations that can exacerbate airway irritation.
Question 3: In a 2 months old infant undergoing surgery for biliary atresia, you would avoid one of the following anaesthetic -
- A. Propofol
- B. Halothane (Correct Answer)
- C. Thiopentone
- D. Sevoflurane
Explanation: ***Halothane*** - **Halothane** is a potent hepatotoxic agent and should be avoided in patients with **biliary atresia** or other liver conditions. - Its metabolism can lead to the formation of **toxic metabolites** that can worsen pre-existing liver dysfunction. *Propofol* - **Propofol** is primarily metabolized by the liver, but its hepatic clearance is generally **high** and less dependent on liver function than some other anesthetics. - It is often used for induction and maintenance of anesthesia in patients with liver disease, with **dose adjustments** as needed. *Thiopentone* - **Thiopentone** (thiopental) is an ultra-short-acting barbiturate primarily eliminated by **hepatic metabolism**. - While it has a good safety profile for liver disease compared to halothane, careful **dose titration** is needed due to potential for prolonged effects with severe hepatic impairment. *Sevoflurane* - **Sevoflurane** is an inhalation anesthetic with minimal hepatic metabolism and a low potential for hepatotoxicity. - It is often considered a **preferred agent** in patients with liver disease due to its favorable metabolic profile.
Question 4: A 50 year old male is posted for elective laparoscopic cholecystectomy. No history of comorbidities. His surgery is scheduled at 2 PM on the day of surgery. Which of the following is against the ASA guidelines for preoperative fasting
- A. Water at 12:00 PM
- B. Black coffee at 5:30 AM
- C. Pancakes at 10:00 AM (Correct Answer)
- D. A non-clear liquid (e.g., orange juice) at 7:30 AM
Explanation: **Pancakes at 10:00 AM** - According to ASA guidelines, the fasting period for solid food is typically **6-8 hours** before surgery. Eating pancakes, which are solid food, at 10:00 AM for a 2:00 PM surgery (4-hour interval) violates this guideline. - This short fasting period for solids increases the risk of **pulmonary aspiration** during induction of anesthesia. *Water at 12:00 PM* - Water is considered a clear liquid, and ASA guidelines typically allow clear liquids until **2 hours** before surgery. Drinking water at 12:00 PM for a 2:00 PM surgery is within these guidelines. - Rapid gastric emptying of clear liquids minimizes the risk of aspiration. *Black coffee at 5:30 AM* - Black coffee is considered a clear liquid, and it is consumed well within the **2-hour** fasting window for clear liquids before a 2:00 PM surgery. - The absence of milk or cream ensures it is treated as a clear liquid, which empties quickly from the stomach. *A non-clear liquid (e.g., orange juice) at 7:30 AM* - Non-clear liquids, such as orange juice, are treated similarly to light meals and generally require a fasting period of **6 hours** before surgery. Drinking orange juice at 7:30 AM for a 2:00 PM surgery (6.5-hour interval) is compliant with these guidelines. - The protein and pulp in non-clear liquids delay gastric emptying compared to clear liquids.
Question 5: Which of the following is the necessary pre-operative investigation which has to be done in a patient with Down's syndrome posted for surgery?
- A. Echocardiography to assess congenital heart defects (Correct Answer)
- B. Cervical spine X-Ray to evaluate atlantoaxial instability
- C. Abdominal ultrasound to detect gastrointestinal anomalies
- D. Brain CT scan to identify structural abnormalities
Explanation: ***Echocardiography to assess congenital heart defects*** - Patients with **Down syndrome (Trisomy 21)** have a high incidence of congenital heart defects, most commonly **atrioventricular septal defects**, which require evaluation prior to surgery due to their anesthetic and surgical implications. - Pre-surgical echocardiography is crucial to identify and characterize these defects, allowing for appropriate perioperative management and optimization of cardiac function. *Cervical spine X-Ray to evaluate atlantoaxial instability* - While **atlantoaxial instability** is a known concern in Down syndrome, particularly important for procedures involving neck manipulation, it is not universally necessary for *every* surgical patient. - Cervical spine imaging is typically reserved for elective procedures where neck manipulation is anticipated or if there are clinical signs suggestive of myelopathy. *Abdominal ultrasound to detect gastrointestinal anomalies* - Gastrointestinal anomalies like **duodenal atresia** or **Hirschsprung disease** are more prevalent in Down syndrome but are usually identified and treated in infancy or childhood due to symptomatic presentation. - Unless there are specific clinical symptoms or a history of unaddressed GI issues, a routine preoperative abdominal ultrasound is generally not indicated. *Brain CT scan to identify structural abnormalities* - Individuals with Down syndrome often have developmental brain differences, but a routine preoperative brain CT scan is not standard practice unless there are neurological symptoms or a history of conditions like seizures or hydrocephalus requiring investigation. - It would not be considered a necessary **pre-operative investigation** for general surgical fitness in the absence of specific indications.
Question 6: According to the DSM-5 criteria for Autism Spectrum Disorder, which of the following is required for diagnosis in children?
- A. Language delay before age 2
- B. Persistent deficits in social communication and interaction (Correct Answer)
- C. Presence of seizure disorder
- D. Intellectual disability
Explanation: ***Persistent deficits in social communication and interaction*** - This is a **core diagnostic criterion** for Autism Spectrum Disorder (ASD) according to DSM-5, encompassing difficulties in social-emotional reciprocity, nonverbal communicative behaviors, and developing/maintaining relationships. - These deficits must be present across **multiple contexts** and not better explained by other conditions. *Language delay before age 2* - While language delay is common in ASD, it is **not a mandatory diagnostic criterion** in the DSM-5; some individuals with ASD may have typical or even advanced language skills. - The focus has shifted from specific language milestones to broader **social communication deficits**. *Presence of seizure disorder* - **Seizures** are a co-occurring medical condition that can affect individuals with ASD, but they are absolutely **not a diagnostic criterion** for the disorder itself. - The presence of a seizure disorder suggests comorbidity, not a defining feature of autism. *Intellectual disability* - **Intellectual disability** frequently co-occurs with ASD (approximately 30-50% of cases), but it is **not a required criterion** for diagnosis. - Many individuals with ASD have average or above-average intellectual abilities.
Question 7: An unconscious child is brought to the casualty. What is the correct sequence of the management?
- A. Circulation, Airway, Breathing
- B. Breathing, Circulation, Airway
- C. Circulation, Breathing, Airway
- D. Airway, Breathing, Circulation (Correct Answer)
Explanation: ***Airway, Breathing, Circulation*** - The **ABC sequence** is the cornerstone of pediatric resuscitation as per **PALS (Pediatric Advanced Life Support) guidelines** - In an unconscious child, a patent **airway** is the absolute first priority - without this, no oxygen can reach the lungs regardless of breathing effort - Once airway patency is ensured, **breathing** must be assessed and supported to provide adequate ventilation and oxygenation - Only after securing airway and breathing should **circulation** be addressed, as effective circulation without oxygenation is futile - This sequence prevents **hypoxic brain injury**, which can occur within 4-6 minutes of oxygen deprivation *Circulation, Airway, Breathing* - This violates the fundamental **ABC principle** of emergency management - Prioritizing **circulation** before establishing a patent **airway** means attempting to circulate deoxygenated blood - Without airway patency, any circulatory support will fail to deliver oxygen to vital organs, leading to **irreversible hypoxic damage** - In pediatric emergencies, respiratory failure is more common than primary cardiac arrest, making airway management even more critical *Breathing, Circulation, Airway* - Attempting to support **breathing** before securing the **airway** is physiologically ineffective - An obstructed airway prevents air entry despite breathing efforts or bag-mask ventilation attempts - This sequence can lead to **gastric distension, aspiration**, and worsening hypoxia - Delays in airway management increase the risk of **cardiac arrest** from prolonged hypoxemia *Circulation, Breathing, Airway* - This sequence dangerously delays **airway management**, the most time-critical intervention - In an unconscious child, airway obstruction from tongue falling back or secretions is common and immediately life-threatening - Without a patent airway, neither breathing support nor circulatory measures can prevent **brain death** from anoxia - Following this sequence contradicts all **international resuscitation guidelines** (PALS, AHA, ERC)
Question 8: A one-year-old child, preterm, and low birth weight with delayed milestones is posted for elective hernia repair. Which of the following statements is true?
- A. Wait for complete neurological evaluation (Correct Answer)
- B. Avoidance of regional anesthesia
- C. Avoidance of combination of inhalational and muscle relaxation
- D. Inhalational agents are contraindicated in this scenario.
Explanation: ***Wait for complete neurological evaluation*** - Preterm, low birth weight, and delayed milestones suggest a heightened risk of **neurological complications** and underscore the importance of a thorough pre-operative neurological assessment. - A comprehensive evaluation can identify specific neurological deficits or vulnerabilities, informing anesthesia planning and **post-operative monitoring** to prevent exacerbation or new onset issues. *Inhalational agents are contraindicated in this scenario.* - **Inhalational agents** are not absolutely contraindicated in preterm, low-birth-weight children with delayed milestones, but their use requires careful titration due to potential for **hemodynamic instability** and increased risk of apnea. - The choice of anesthetic technique depends on the child's specific condition and the surgeon's preference, with a focus on **neuroprotective strategies** and minimizing risks. *Avoidance of regional anesthesia* - **Regional anesthesia** can be beneficial in preterm infants for hernia repair by potentially reducing the need for systemic opioids and their associated side effects, as well as lowering the incidence of **post-operative apnea**. - Its use, however, requires careful consideration of the child's coagulation status, cardiovascular stability, and the expertise of the anesthesiologist in performing blocks in this vulnerable population. *Avoidance of combination of inhalational and muscle relaxation* - The combination of **inhalational agents** and **muscle relaxants** is routinely used in pediatric anesthesia for appropriate surgical conditions and is not inherently contraindicated in this population. - Careful titration of both agents is essential to minimize their respective side effects, such as cardiovascular depression from inhalational agents and prolonged muscle weakness from neuromuscular blockers, especially in a child with baseline neurological challenges.
Question 9: Modified Mallampati grading is used in assessment of -
- A. Difficulty of intubation (Correct Answer)
- B. Obstruction of the airway
- C. Aspiration-related death
- D. Endotracheal intubation procedure
Explanation: ***Difficulty of intubation*** - The **Modified Mallampati score** assesses the visibility of pharyngeal structures, which directly correlates with the ease or difficulty of performing **direct laryngoscopy** and **endotracheal intubation**. - A higher Mallampati class (e.g., III or IV) indicates less visibility of the soft palate, uvula, and pillars, suggesting a more difficult airway and increased likelihood of a challenging intubation. *Obstruction of the airway* - While a high Mallampati score might indirectly indicate potential for **airway obstruction** during anesthesia due to anatomical features, its primary purpose is not to diagnose or quantify existing airway obstruction. - Airway obstruction is more directly assessed by monitoring breathing sounds, respiratory effort, and oxygen saturation. *Aspiration-related death* - The **Mallampati score** helps predict the difficulty of securing the airway but does not directly assess the risk of **aspiration**. - Aspiration risk is evaluated based on factors like gastric contents, gag reflex, and patient positioning. *Endotracheal intubation procedure* - The **Modified Mallampati score** helps in **planning the intubation procedure** by identifying potential difficulties but is not a measure of the intubation procedure itself. - It is a **pre-procedure assessment tool** to gauge airway anatomy, not a description or evaluation of the steps involved in endotracheal intubation.
Question 10: Juvenile polyp is a type of which of the following?
- A. Hamartomatous polyp (Correct Answer)
- B. Lymphoid polyp
- C. Hyperplastic type
- D. Inflammatory polyp
Explanation: ***Hamartomatous polyp*** - Juvenile polyps are classified as **hamartomatous polyps**, characterized by an excessive growth of tissue normally present in the area. - They are typically found in children and can be associated with **Juvenile Polyposis Syndrome** if multiple polyps are present [1]. *Hyperplastic type* - Hyperplastic polyps are usually small, **sessile polyps** found mainly in the colon and are not associated with significant risk of malignancy. - They do not have the **hamartomatous** features characteristic of juvenile polyps. *Lymphoid polyp* - Lymphoid polyps are composed primarily of **lymphoid tissue** and are often incidental findings in children; they are not the same as juvenile polyps. - These polyps are more common in the **ileum** and do not exhibit the same histological characteristics as hamartomatous polyps. *Inflammatory polyp* - Inflammatory polyps arise as a result of **inflammation** and are commonly associated with conditions like **ulcerative colitis**. - They differ from juvenile polyps, which arise from abnormal growth and are typically **non-inflammatory** in nature. **References:** [1] Kumar V, Abbas AK, et al.. Robbins and Cotran Pathologic Basis of Disease. 9th ed. The Gastrointestinal Tract, p. 813.
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