Question 11: Koplik spots are seen in?
- A. Rubella
- B. Mumps
- C. Varicella
- D. Measles (Correct Answer)
Explanation: ***Measles***
- **Koplik spots** are pathognomonic rash that appears as small, white spots with a bluish-white center on an erythematous base on the **buccal mucosa** opposite the second molars.
- They typically appear 2-3 days before the onset of the characteristic maculopapular rash, during the **prodromal phase** of measles (rubeola).
*Rubella*
- Rubella, or **German measles**, presents with a milder rash, **lymphadenopathy**, and mild fever.
- It does not cause Koplik spots; instead, **Forchheimer spots** (petechiae on the soft palate) may be seen, but these are less specific.
*Mumps*
- Mumps is characterized primarily by **parotitis** (swelling of the salivary glands), fever, and headache.
- It does not present with Koplik spots or any characteristic oral mucosal lesions.
*Varicella*
- Varicella, or **chickenpox**, is characterized by a **vesicular rash** that progresses from macules to papules to vesicles to crusts, appearing in crops.
- It does not involve Koplik spots; the rash is typically generalized and pruritic.