NEET-PG 2020 Practice Questions

Q: The patient is presenting with pain around the base of the thumb. Which tendons are likely involved?

APL & EPB. ***APL & EPB*** - Pain around the base of the thumb, especially with movement, is characteristic of De Quervain's tenosynovitis [1]. This condition involves the **abductor pollicis longus (APL)** and **extensor pollicis brevis (EPB)** tendons [1]. - These two tendons share a common synovial sheath as they pass through the first dorsal compartment of the wrist, making them susceptible to inflammation and friction [1]. *APB & EPL* - **APB (Abductor Pollicis Brevis)** is an intrinsic hand muscle found in the thenar eminence, primarily involved in thumb abduction, and is not typically associated with De Quervain's tenosynovitis. - **EPL (Extensor Pollicis Longus)** is part of the third dorsal compartment and its tendon crosses over the other thumb tendons, and is not inflamed in De Quervain's tenosynovitis. *APB & EPB* - As mentioned, **APB (Abductor Pollicis Brevis)** is an intrinsic hand muscle, not involved in De Quervain's tenosynovitis. - While **EPB (Extensor Pollicis Brevis)** is involved, its combination with APB incorrectly identifies the primary tendons affected in the first dorsal compartment. *APL & EPL* - **APL (Abductor Pollicis Longus)** is one of the correct tendons involved. - **EPL (Extensor Pollicis Longus)** belongs to the third dorsal compartment of the wrist and is not typically affected in De Quervain's tenosynovitis, differentiating it from the tendons in the first dorsal compartment [1].

Q: Identify the type of cartilage shown in the image.

Fibrocartilage. ***Fibrocartilage*** - The image displays **chondrocytes** arranged in rows between bundles of **collagen fibers**, characteristic of fibrocartilage. This structure provides high tensile strength and shock absorption. - Unlike other cartilage types, fibrocartilage lacks a distinct perichondrium and is found in structures requiring extreme strength, such as intervertebral discs and menisci. *Hyaline cartilage* - Hyaline cartilage has an amorphous, **glassy matrix** with chondrocytes typically arranged in small groups (isogenous groups) within lacunae, without prominent collagen bundles. - It is found in articular surfaces, tracheal rings, and the costal cartilages, providing smooth, low-friction surfaces. *Elastic cartilage* - Elastic cartilage is characterized by a high concentration of **elastic fibers** within its matrix, giving it flexibility and resilience. - Chondrocytes are typically scattered and the matrix stains darker due to the elastic fibers, which are not apparent in the image. *Dense connective tissue* - While dense connective tissue contains abundant **collagen fibers**, it lacks chondrocytes in lacunae, instead containing fibroblasts. - The presence of chondrocytes in the image confirms this is cartilage, not dense connective tissue.

Q: Which of the following diseases is primarily water-related?

Cholera. ***Cholera*** - Cholera is caused by the bacterium **Vibrio cholerae**, which is typically transmitted through the consumption of **contaminated water or food**. - This disease is a classic example of a **waterborne illness**, with outbreaks often linked to inadequate sanitation and unsafe drinking water. *Yellow fever* - Yellow fever is a **viral hemorrhagic disease** transmitted by infected **mosquitoes**, primarily Aedes aegypti. - While mosquitoes may breed in water, the disease itself is not directly transmitted through water consumption. *Scabies* - Scabies is a **skin infestation** caused by the mite **Sarcoptes scabiei**, which burrows into the outer layer of the skin. - Transmission occurs through **direct, prolonged skin-to-skin contact**, not through water. *Dysentery* - Dysentery is an **intestinal inflammation** causing bloody diarrhea, which can be caused by bacteria (e.g., Shigella) or amoebas (e.g., Entamoeba histolytica). - Although it can be transmitted through contaminated water or food, it is a broader term for a symptom, and **cholera is more exclusively and primarily focused on water-borne transmission mechanisms**.

Q: As per the Sustainable Development Goals, what is the target for Maternal Mortality Ratio (MMR)?

< 70 per 100,000 live births. ***< 70 per 100,000 live births*** - **Sustainable Development Goal (SDG) 3.1** specifically targets reducing the global maternal mortality ratio to less than **70 per 100,000 live births** by 2030. - This target aims to address the significant disparities in maternal mortality rates observed across different regions and countries. *< 100 per 100,000 live births* - While this represents an improvement over current global averages, it is **not the specific target set by SDG 3.1** for maternal mortality. - The SDGs establish a more ambitious threshold to ensure greater progress in maternal health outcomes. *< 7 per 1,000 live births* - This value is equivalent to **700 per 100,000 live births**, which is significantly higher than the SDG target and represents a **much higher maternal mortality rate**. - This option reflects a misunderstanding of the scale and denominator used for maternal mortality ratios in the SDGs. *< 10 per 1,000 live births* - This value is equivalent to **1,000 per 100,000 live births**, which is also **significantly higher than the SDG target**. - This option shows a similar misconception regarding the magnitude and proper reporting of maternal mortality ratios.

Q: Esophageal manometry was performed - it revealed panesophageal pressurization with distal contractile integrity as >450mm Hg pressure in the body. What will be the diagnosis?

Type 3 achalasia. The diagnosis is Type 3 achalasia. This condition is characterized by panesophageal pressurization, indicating diffuse, simultaneous contractions throughout the esophagus. The high distal contractile integrity (>450 mmHg pressure) further supports Type 3 achalasia, which involves significant spastic contractions. In contrast, while high-resolution manometry allows for the accurate classification of these motility abnormalities [1], other types present differently. Type 1 achalasia (classic achalasia) is marked by failed esophageal peristalsis and absent or minimal esophageal pressurization [1]. The primary characteristic is incomplete or absent lower esophageal sphincter (LES) relaxation, not hypercontractility [1]. Type 2 achalasia is identified by esophageal panesophageal pressurization (simultaneous contractions), but with normal to high contractile pressures, not the extremely high values seen here. Jackhammer esophagus involves hypercontractility (distal contractile integral >8000 mmHg·cm·s) and is characterized by rapid, repetitive, and fragmented contractions, rather than the diffuse panesophageal pressurization and spasticity typical of Type 3 achalasia [2].

Q: Which antibody is not transmitted from mother to baby?

IgA antibodies. ***IgA antibodies*** - While IgA is found in breast milk and provides **passive immunity** to the infant's gastrointestinal tract, it is **not transferred across the placenta** to the fetus. - This antibody has a larger molecular structure and is primarily involved in **mucosal immunity**, making it unsuitable for transplacental transfer. *Diphtheria IgG antibodies* - **IgG antibodies**, including those for diphtheria, are actively transported across the **placenta** from mother to fetus during the third trimester. - This transfer provides the newborn with **passive immunity** against diphtheria during the first few months of life. *Tetanus IgG antibodies* - Similar to diphtheria IgG, **tetanus IgG antibodies** are efficiently transported across the **placenta** from mother to baby. - This offers crucial **passive protection** against tetanus, particularly important after birth. *Measles IgG antibodies* - **Measles IgG antibodies** from a vaccinated or previously infected mother cross the **placenta** to the fetus. - This maternal transfer provides temporary **passive immunity** to the newborn against measles.

Q: A 35-year-old female experiences a tingling sensation in her arm after watching TV for long hours with her hands under her head. Which type of nerve fibers is most likely to be affected due to this position?

A-beta (Aβ) sensory nerve fibers. ***A-beta (Aβ) sensory nerve fibers*** - The tingling sensation (paresthesia) described is a classic symptom of **A-beta fiber compression**. - **A-beta fibers** are large, myelinated sensory fibers that transmit light touch, pressure, vibration, and proprioception. - These fibers are **most susceptible to mechanical compression** due to their position and structure. - Positioning the hands under the head for extended periods compresses superficial nerves, causing temporary A-beta fiber dysfunction, which manifests as the characteristic "pins and needles" sensation. *B-fibers (autonomic)* - **B-fibers** are preganglionic autonomic fibers that mediate visceral functions, such as organ control and glandular secretions. - Compression of these fibers would lead to symptoms related to autonomic dysfunction (e.g., changes in sweating, blood pressure), not a tingling sensation in the arm. *C-fibers (pain and temperature)* - **C-fibers** are unmyelinated fibers that transmit slow, dull, aching pain and contribute to temperature sensation. - They are **less susceptible to compression** than larger myelinated fibers. - The primary sensation described (tingling/paresthesia) is characteristic of large myelinated fiber (A-beta) dysfunction, not C-fiber involvement. *Sympathetic nerve fibers* - **Sympathetic nerve fibers** regulate involuntary functions like heart rate, blood pressure, and sweating. - Their compression would cause symptoms such as changes in skin temperature, altered sweating, or blood vessel constriction (Horner's syndrome if severe), not a tingling sensation.

Q: Which of the following is referred to as the "Window of the limbic system"?

Thalamus. ***Thalamus*** - The thalamus is often referred to as the **"relay station"** of the brain, processing and relaying most **sensory information** (except smell) to the cerebral cortex. - Due to its extensive connections with various limbic structures and its role in integrating and filtering emotional and motivational information before it reaches conscious awareness, it's considered the **"window of the limbic system"**. *Hypothalamus* - The hypothalamus primarily controls **autonomic functions** and maintains **homeostasis**, such as regulating temperature, hunger, thirst, and sleep cycles. - While it has strong connections with the limbic system, its main role is executive autonomic control rather than sensory integration. *Amygdala* - The amygdala is critically involved in processing **emotions**, particularly **fear** and **aggression**, and plays a key role in emotional memory. - It's a central component *within* the limbic system, but it doesn't serve as a general window or relay for the entire system's input. *Hippocampus* - The hippocampus is primarily responsible for **memory formation** (especially new episodic memories) and spatial navigation. - It is an important limbic structure, but its function is more specific to memory rather than being a gateway for broader limbic system activity.

Q: In a patient with parathyroid adenoma, how do we confirm the removal of the correct gland after surgery?

50% reduction in PTH after 10 minutes. ***50% reduction in PTH after 10 minutes*** - Intraoperative **PTH monitoring** is crucial for confirming complete removal of hyperfunctioning parathyroid tissue during parathyroidectomy. - A successful surgery is indicated by a **≥50% drop** in PTH levels from the baseline (pre-excision) or highest post-excision level within **10 minutes** of gland removal. *25% reduction in PTH after 10 minutes* - A **25% reduction** in PTH after 10 minutes is generally considered **insufficient** to confirm successful removal of the hyperfunctioning gland. - This level of reduction may suggest incomplete removal or the presence of additional hypersecreting tissue. *25% reduction in PTH after 5 minutes* - While an initial drop may be observed, a **25% reduction after only 5 minutes** without further significant decline by 10 minutes is often not indicative of successful surgery. - The standard MIBI-scan-guided protocol or the Miami criteria require a more substantial and sustained drop. *50% reduction in PTH after 5 minutes* - A rapid and significant **50% reduction after 5 minutes** of excision is a good sign but the gold standard for intraoperative PTH monitoring typically requires the **10-minute post-excision** sample to confirm the sustained drop. - The **Miami Criteria**, a widely accepted protocol, uses the 10-minute post-excision time point as a critical determinant.

Q: A pregnant female had meconium-stained liquor and underwent emergency LSCS. A few days later, her condition deteriorated, and an ultrasound showed edematous bowels. What is the most likely cause of her condition?

Paralytic ileus. ***Paralytic ileus*** - **Paralytic ileus**, often called **postoperative ileus**, is a common complication after abdominal surgeries like **LSCS**, especially when associated with complications like meconium-stained liquor. - The combination of **meconium-stained liquor** (indicating fetal distress/inflammation) and **emergency LSCS** increases the risk for a prolonged inflammatory response post-surgery, leading to intestinal paralysis and **edematous bowels**. - Ultrasound findings of **edematous bowels** without signs of mechanical obstruction support this diagnosis. *Adhesive intestinal obstruction* - **Adhesive intestinal obstruction** usually occurs later, weeks to years after surgery, as **adhesions** form and contract. - While possible, it is less likely to present acutely a "few days later" after an initial surgery compared to **paralytic ileus**. *Intra-abdominal abscess* - An **intra-abdominal abscess** would typically cause localized pain, fever, and signs of infection with more focal findings on imaging. - The primary observation of **edematous bowels** points more directly to diffuse bowel dysfunction rather than a localized collection. *Intestinal perforation* - **Intestinal perforation** would present with acute peritonitis, free fluid/air on imaging, severe abdominal pain, and signs of sepsis. - While edematous bowels can be present, the clinical picture would be more dramatic with peritoneal signs rather than the subacute deterioration described here.

Question 1

The patient is presenting with pain around the base of the thumb. Which tendons are likely involved?

Accepted Answer

APL & EPB

Answer

APB & EPL

Answer

APB & EPB

Answer

APL & EPL

Question 2

Identify the type of cartilage shown in the image.

Accepted Answer

Fibrocartilage

Answer

Hyaline cartilage

Answer

Elastic cartilage

Answer

Dense connective tissue

Question 3

Which of the following diseases is primarily water-related?

Accepted Answer

Cholera

Answer

Scabies

Answer

Yellow fever

Answer

Dysentery

Question 4

As per the Sustainable Development Goals, what is the target for Maternal Mortality Ratio (MMR)?

Accepted Answer

< 70 per 100,000 live births

Answer

< 100 per 100,000 live births

Answer

< 7 per 1,000 live births

Answer

< 10 per 1,000 live births

Question 5

Esophageal manometry was performed - it revealed panesophageal pressurization with distal contractile integrity as >450mm Hg pressure in the body. What will be the diagnosis?

Accepted Answer

Type 3 achalasia

Answer

Type 2 achalasia

Answer

Jackhammer esophagus

Answer

Type 1 achalasia (classic achalasia)

Question 6

Which antibody is not transmitted from mother to baby?

Accepted Answer

IgA antibodies

Answer

Tetanus IgG antibodies

Answer

Diphtheria IgG antibodies

Answer

Measles IgG antibodies

Question 7

A 35-year-old female experiences a tingling sensation in her arm after watching TV for long hours with her hands under her head. Which type of nerve fibers is most likely to be affected due to this position?

Accepted Answer

A-beta (Aβ) sensory nerve fibers

Answer

B - fibers (autonomic)

Answer

C - fibers (pain and temperature)

Answer

Sympathetic nerve fibers

Question 8

Which of the following is referred to as the "Window of the limbic system"?

Accepted Answer

Thalamus

Answer

Hypothalamus

Answer

Hippocampus

Answer

Amygdala

Question 9

In a patient with parathyroid adenoma, how do we confirm the removal of the correct gland after surgery?

Accepted Answer

50% reduction in PTH after 10 minutes

Answer

25% reduction in PTH after 10 minutes

Answer

25% reduction in PTH after 5 minutes

Answer

50% reduction in PTH after 5 minutes

Question 10

A pregnant female had meconium-stained liquor and underwent emergency LSCS. A few days later, her condition deteriorated, and an ultrasound showed edematous bowels. What is the most likely cause of her condition?

Accepted Answer

Paralytic ileus

Answer

Adhesive intestinal obstruction

Answer

Intra-abdominal abscess

Answer

Intestinal perforation

NEET-PG 2020

Anatomy

Community Medicine

Internal Medicine

Microbiology

Physiology

Surgery