Anatomy
5 questionsWhich of the following is derived from endoderm?
Sensory supply of the palm is from which nerves?
Ophthalmic artery is a branch of:
What is the anatomical significance of the Rhinion in relation to the osseocartilaginous junction?
Primary and secondary palates are divided by
NEET-PG 2012 - Anatomy NEET-PG Practice Questions and MCQs
Question 231: Which of the following is derived from endoderm?
- A. Gall bladder (Correct Answer)
- B. Lens
- C. Spleen
- D. Lymph nodes
Explanation: ***Gall bladder*** - The **gallbladder**, along with other organs of the **gastrointestinal tract** such as the liver, pancreas, and epithelial lining of the digestive and respiratory systems, originates from the **endoderm** [1]. - The endoderm forms the primitive gut tube, from which these accessory digestive organs bud off. *Lens* - The **lens of the eye** is derived from the **surface ectoderm**, which invaginates to form the lens vesicle. - This contrasts with the neural ectoderm, which forms the neural tube and retina. *Spleen* - The **spleen** is derived from the **mesoderm**, specifically from mesenchymal cells in the dorsal mesentery of the stomach. - It is involved in blood filtration and immune responses, making it a lymphoid organ. *Lymph nodes* - **Lymph nodes** are primarily derived from the **mesoderm**, specifically from specialized mesenchymal cells that form their connective tissue capsule and stroma. - The immune cells within the lymph nodes, such as lymphocytes, originate from hematopoietic stem cells that migrate into these developing structures.
Question 232: Sensory supply of the palm is from which nerves?
- A. Median nerve and Radial nerve
- B. Radial nerve and ulnar nerve
- C. Ulnar nerve and Median nerve (Correct Answer)
- D. Musculocutaneous nerve and Radial nerve
Explanation: **Ulnar nerve and Median nerve** *(Correct)* - The **median nerve** provides sensory innervation to the lateral palm, including the thumb, index, middle, and radial half of the ring finger [1]. - The **ulnar nerve** supplies sensory innervation to the medial palm, including the little finger and the ulnar half of the ring finger [1]. - Together, these two nerves provide complete sensory coverage of the palm [1]. *Median nerve and Radial nerve* (Incorrect) - While the **median nerve** innervates a significant portion of the palm, the **radial nerve** primarily supplies the dorsal aspect of the hand and a small area of the thenar eminence, not the entire palm. - The radial nerve's sensory supply to the palm is usually limited to a very small area at the base of the thumb. - This combination does not provide complete palmar sensory coverage. *Radial nerve and ulnar nerve* (Incorrect) - The **radial nerve** mainly supplies the dorsum of the hand and digits, with minimal palmar contribution, making this option incorrect for primary palmar sensory supply. - The **ulnar nerve** does innervate part of the palm, but the combination with the radial nerve for complete palmar supply is inaccurate. - The median nerve, not the radial nerve, is the other major contributor to palmar sensation. *Musculocutaneous nerve and Radial nerve* (Incorrect) - The **musculocutaneous nerve** primarily innervates the lateral aspect of the forearm (as the lateral antebrachial cutaneous nerve) and does not contribute to the sensory supply of the palm. - The **radial nerve** also has a limited role in palmar sensation. - Neither of these nerves provides significant sensory innervation to the palm.
Question 233: Ophthalmic artery is a branch of:
- A. Cavernous part of ICA
- B. Cerebral part of ICA (Correct Answer)
- C. MCA
- D. Facial artery
Explanation: ***Cerebral part of ICA*** - The **ophthalmic artery** is typically the first major branch off the **internal carotid artery (ICA)** once it exits the cavernous sinus and enters the cranial cavity. - This segment of the ICA is also known as the supraclinoid or **cerebral part**, underscoring its proximity to the brain. *Cavernous part of ICA* - The **cavernous part of the ICA** is located within the cavernous sinus and typically gives off smaller branches such as the **meningohypophyseal trunk** and the **inferolateral trunk**, which supply structures within and around the sinus. - The ophthalmic artery emerges after the ICA exits the cavernous sinus, not from within it. *MCA* - The **middle cerebral artery (MCA)** is a major terminal branch of the internal carotid artery, supplying large parts of the cerebrum. - It does not give rise to the ophthalmic artery, which branches off the ICA before the ICA bifurcates into the MCA and anterior cerebral artery. *Facial artery* - The **facial artery** is a branch of the **external carotid artery**, supplying structures of the face. - The ophthalmic artery is a primary supply to the orbit and is derived from the internal carotid artery, a completely separate vascular system.
Question 234: What is the anatomical significance of the Rhinion in relation to the osseocartilaginous junction?
- A. Nasion
- B. Rhinion (Correct Answer)
- C. Radix
- D. Columella
Explanation: ***Correct Answer: Rhinion*** - The **rhinion** is the **most prominent anterior point of the nasal bone**, often palpable as a slight bump or angulation on the dorsum of the nose. - It marks the anatomical location of the **osseocartilaginous junction** of the nasal dorsum, where the bony nasal framework transitions to the cartilaginous framework. - This is the key anatomical landmark that defines the transition from bone to cartilage in the external nose. *Incorrect: Nasion* - The **nasion** is located at the **root of the nose**, specifically at the most anterior and superior point of the nasofrontal suture. - It is a bony landmark and does not directly relate to the osseocartilaginous junction of the nasal dorsum. *Incorrect: Radix* - The **radix** (or nasal root) refers to the **uppermost part of the nose**, corresponding to the nasion. - It defines the point where the nose begins to project from the forehead and is a bony landmark, not directly related to the osseocartilaginous junction. *Incorrect: Columella* - The **columella** is the **fleshy, narrow strip of tissue that separates the nostrils**. - It forms the inferior segment of the nasal septum and is composed of skin, soft tissue, and the medial crura of the alar cartilages, thus having no direct relation to the osseocartilaginous junction of the nasal dorsum.
Question 235: Primary and secondary palates are divided by
- A. Greater palatine foramen
- B. Canine teeth
- C. Alveolar arch
- D. Incisive foramen (Correct Answer)
Explanation: ***Incisive foramen*** - The **incisive foramen** is an anatomical landmark located just posterior to the central incisors, and it marks the boundary between the developmentally distinct primary and secondary palates. - The **primary palate** develops from the median palatine process, while the **secondary palate** develops from the palatal shelves of the maxillary prominences [1]. *Greater palatine foramen* - The **greater palatine foramen** is located near the posterior border of the hard palate, transmitting the greater palatine nerve and vessels. - It lies within the **secondary palate** and does not delineate the boundary between the primary and secondary palatal structures. *Canine teeth* - The **canine teeth** are part of the dental arch and play a role in mastication. - While located in the anterior part of the oral cavity, they are not a developmental or anatomical boundary marker for palatal divisions [1]. *Alveolar arch* - The **alveolar arch** is the bone that supports the teeth, forming the curved ridge of the maxilla and mandible [1]. - It is distinct from the palate and does not serve as a divider between the primary and secondary palatal components.
Anesthesiology
1 questionsWhich of the following is true about coeliac plexus block?
NEET-PG 2012 - Anesthesiology NEET-PG Practice Questions and MCQs
Question 231: Which of the following is true about coeliac plexus block?
- A. Usually done unilaterally
- B. Most common side effects include diarrhea and hypotension (Correct Answer)
- C. Located retroperitoneally at the level of L3
- D. Useful for painful conditions of the lower abdomen
Explanation: ***Most common side effects include diarrhea and hypotension*** - A coeliac plexus block interrupts **sympathetic innervation** to the upper abdominal organs, which can lead to parasympathetic dominance. - This imbalance often results in **increased gastrointestinal motility (diarrhea)** and **vasodilation (hypotension)** as common side effects. *Located retroperitoneally at the level of L3* - The coeliac plexus is typically located **retroperitoneally** at the level of the **T12-L1 vertebrae**, not L3. - Its position is generally superior to the renal arteries, which are closer to L1-L2. *Usually done unilaterally* - A coeliac plexus block is almost always performed **bilaterally** or with a single posterior approach aiming for bilateral spread to effectively block the plexus. - The coeliac plexus is an extensive network, and a unilateral block would likely provide inadequate pain relief. *Useful for painful conditions of the lower abdomen* - The coeliac plexus primarily innervates **upper abdominal organs** (e.g., pancreas, liver, stomach, small intestine, kidneys, adrenal glands). - It is therefore generally **ineffective for lower abdominal pain**, which is innervated by different sympathetic plexuses (e.g., superior and inferior hypogastric plexuses).
Biochemistry
3 questionsUric acid is formed by?
Which RNA is used in RNA splicing?
Which of the following does not play a role in protein synthesis?
NEET-PG 2012 - Biochemistry NEET-PG Practice Questions and MCQs
Question 231: Uric acid is formed by?
- A. Catabolism of proteins
- B. Catabolism of ketones
- C. Catabolism of purines (Correct Answer)
- D. Catabolism of pyrimidines
Explanation: ***Catabolism of purines*** - **Uric acid** is the final breakdown product of **purine metabolism** in humans. - **Purines** (adenine and guanine) are components of nucleic acids (DNA and RNA) and are broken down through a series of enzymatic steps, ultimately forming uric acid. *Catabolism of proteins* - The catabolism of proteins leads to the formation of **amino acids**, which are then further broken down to produce **urea** (via the urea cycle) as the main nitrogenous waste product, not uric acid. - Protein breakdown primarily provides energy or building blocks for new proteins. *Catabolism of ketones* - The catabolism of ketones occurs when the body uses **fatty acids** for energy, often during fasting or uncontrolled diabetes. - Key products are **acetyl-CoA** and energy, not uric acid. *Catabolism of pyrimidines* - The catabolism of pyrimidines (cytosine, thymine, and uracil) produces compounds like **beta-alanine** and **ammonia**. - Unlike purines, pyrimidine breakdown does not result in uric acid formation.
Question 232: Which RNA is used in RNA splicing?
- A. mRNA
- B. tRNA
- C. rRNA
- D. Small nuclear RNA (snRNA) (Correct Answer)
Explanation: ***Small nuclear RNA (snRNA)*** - **snRNAs** are key components of **spliceosomes**, the molecular machines that catalyze the removal of introns from pre-mRNA. - They bind to specific sequences within the pre-mRNA and facilitate the splicing reactions. *mRNA* - **mRNA (messenger RNA)** carries the genetic code from DNA to the ribosomes for **protein synthesis**. - While it is the molecule that gets spliced, it does not directly participate in the splicing machinery itself. *rRNA* - **rRNA (ribosomal RNA)** is a structural and catalytic component of **ribosomes**, where protein synthesis occurs. - It plays no direct role in the process of RNA splicing. *tRNA* - **tRNA (transfer RNA)** molecules are responsible for carrying specific **amino acids** to the ribosome during protein synthesis. - They are involved in translation, not in the processing of RNA by splicing.
Question 233: Which of the following does not play a role in protein synthesis?
- A. m-RNA
- B. ATP
- C. Intron (Correct Answer)
- D. Exon
Explanation: ***Intron*** - Introns are **non-coding regions** within a gene that are transcribed into RNA but are subsequently **spliced out** before translation. - They do not carry genetic information for protein synthesis; their removal ensures the correct sequence of amino acids is produced. *Exon* - Exons are the **coding regions** of a gene that contain the genetic information for protein synthesis. - After introns are removed, exons are ligated together to form the **mature mRNA** that is translated into protein. *m-RNA* - **Messenger RNA (mRNA)** carries the genetic code from DNA in the nucleus to the ribosomes in the cytoplasm. - It serves as the **template** for protein synthesis through the process of translation. *ATP* - **Adenosine triphosphate (ATP)** provides the **energy** required for various steps in protein synthesis, including mRNA transcription, amino acid activation, and ribosome movement. - It is a crucial energy currency that fuels the process of forming peptide bonds and assembling the polypeptide chain.
Physiology
1 questionsWhich of the following contains the PRIMARY central chemoreceptors responsible for detecting CO2 and pH changes in cerebrospinal fluid?
NEET-PG 2012 - Physiology NEET-PG Practice Questions and MCQs
Question 231: Which of the following contains the PRIMARY central chemoreceptors responsible for detecting CO2 and pH changes in cerebrospinal fluid?
- A. Medulla (Correct Answer)
- B. Baroreceptors in carotid sinus
- C. Peripheral chemoreceptors in carotid bodies
- D. All of the above
Explanation: ***Medulla*** - The **medulla oblongata** in the brainstem houses the primary central chemoreceptors. - These chemoreceptors are located on the **ventral surface of the medulla** and are highly sensitive to changes in the **pH of the cerebrospinal fluid (CSF)**, which is indirectly affected by the partial pressure of carbon dioxide (PCO2) in arterial blood. - CO2 diffuses across the blood-brain barrier, combines with water to form H+ ions, which directly stimulate these central chemoreceptors. *Baroreceptors in carotid sinus* - **Baroreceptors** primarily detect changes in **arterial blood pressure**, not CO2 or pH levels. - They are located in the carotid sinus and aortic arch and are involved in cardiovascular reflexes, not direct chemoreception for respiratory drive. *Peripheral chemoreceptors in carotid bodies* - **Peripheral chemoreceptors** in the carotid bodies (and aortic bodies) detect changes in **arterial blood O2, CO2, and pH**. - However, they are **peripheral**, not central chemoreceptors, and are the primary detectors of **hypoxemia**. - They contribute to respiratory drive but are secondary to central chemoreceptors for CO2 detection. *All of the above* - This option is incorrect because only the **medulla** contains the primary central chemoreceptors for CO2 and pH detection in CSF. - Baroreceptors detect blood pressure, and peripheral chemoreceptors are not central chemoreceptors.