NEET-PG 2012

1213 Questions — Page 115 of 122

Internal Medicine

3 questions

Q1141

In a severely anaemic pregnant patient presenting with cardiac failure, what is the most appropriate choice of transfusion?

Q1142

Tuberculosis of the spine; what is the most common site affected?

Q1143

In axillary nerve paralysis, which of the following statements is false?

NEET-PG 2012 - Internal Medicine NEET-PG Practice Questions and MCQs

Question 1141: In a severely anaemic pregnant patient presenting with cardiac failure, what is the most appropriate choice of transfusion?

A. Platelets
B. Packed cells (Correct Answer)
C. Whole blood
D. Exchange transfusion

Explanation: ***Packed cells*** - **Packed red blood cells (PRBCs)** increase **oxygen-carrying capacity** with minimal volume expansion, which is crucial in patients with cardiac compromise [1]. - Slow infusion of PRBCs, often with a **diuretic**, can improve anaemia and cardiac function while preventing **fluid overload**. *Platelets* - **Platelets** are primarily transfused for **thrombocytopenia** or **platelet dysfunction** to prevent or treat bleeding. - They do not address the low haemoglobin and oxygen-carrying deficit directly contributing to cardiac failure in an anaemic patient. *Whole blood* - **Whole blood** contains plasma, which can significantly increase circulatory volume and worsen **cardiac failure** in patients already struggling with fluid balance. - While it does provide red cells, the added volume makes it a less safe option compared to packed cells in this scenario. *Exchange transfusion* - An **exchange transfusion** involves removing a patient's blood and replacing it with donor blood, typically used for severe conditions like **sickle cell crisis** or **severe hyperbilirubinemia** [2]. - This procedure is complex and carries higher risks, and is not the first-line treatment for anaemia-induced cardiac failure in pregnancy.

Question 1142: Tuberculosis of the spine; what is the most common site affected?

A. Sacral
B. Dorsolumbar (Correct Answer)
C. Lumbosacral
D. Cervical

Explanation: ***94ed055d-c7da-4d18-a2fd-52720dfe8b6e*** - The **dorsolumbar (thoracolumbar)** region is the most common site of **spinal tuberculosis (Pott's disease)** [1] due to its high vascularity, facilitating hematogenous spread. - **Spinal tuberculosis** typically affects the vertebral bodies, leading to their destruction, kyphosis (angular deformity), and potentially neurological deficits [1]. *aebdfe6c-98dc-4073-892f-bb24d047bab4* - The **sacral** region can be affected by **tuberculosis**, but it is considerably less common than the thoracolumbar region. - Involvement of the sacrum is often associated with **direct extension** from adjacent structures, such as the sacroiliac joint, rather than primary vertebral involvement. *15c1feef-e3ca-496f-a180-127d52b77bfa* - **Cervical spine tuberculosis** is relatively rare, accounting for a small percentage of all spinal tuberculosis cases. - While possible, it presents with specific challenges due to the proximity of vital neurological and vascular structures. *d05d4d13-bb83-4f26-aa2d-c9c0203d299c* - The **lumbosacral region** (L5-S1) can be involved in **tuberculosis**, but it is less frequently affected than the thoracolumbar region. - While the lumbar spine is a common site, the entire lumbosacral region as a single entity is not the most common spot for spinal TB.

Question 1143: In axillary nerve paralysis, which of the following statements is false?

A. Extension of shoulder with arm abducted to 90 degrees is impossible (Correct Answer)
B. Deltoid muscle is wasted
C. Small area of numbness is present over the shoulder region
D. Patient cannot initiate abduction

Explanation: Extension of shoulder with arm abducted to 90 degrees is impossible - The **axillary nerve** primarily innervates the **deltoid** and **teres minor muscles**. [2] - While axillary nerve paralysis would affect abduction and external rotation, the ability to *extend* the shoulder from an abducted position is mainly a function of muscles like the **posterior deltoid** (also innervated by axillary nerve to varying degrees) and latissimus dorsi, and its impossibility is not a definitive and exclusive sign of axillary nerve paralysis, as other muscles contribute to extension. *Deltoid muscle is wasted* - The **deltoid muscle** is the principal muscle supplied by the **axillary nerve**. [2] - Paralysis leads to **denervation atrophy**, causing visible wasting and weakness of the deltoid. [1] *Small area of numbness is present over the shoulder region* - The **axillary nerve** gives rise to the **upper lateral cutaneous nerve of the arm**. - Damage to the nerve results in sensory loss in a small, circumscribed area over the **deltoid insertion**. [2] *Patient cannot initiate abduction* - The **deltoid muscle**, innervated by the **axillary nerve**, is the primary abductor of the arm after the initial 0-15 degrees (supraspinatus). [2] - Paralysis of the deltoid significantly impairs or prevents the initiation and execution of **shoulder abduction**.

Obstetrics and Gynecology

2 questions

Q1141

Which of the following statements about tuberculosis (TB) of the uterus is NOT true?

Q1142

What is the most common cause of hydrops fetalis in current medical practice?

NEET-PG 2012 - Obstetrics and Gynecology NEET-PG Practice Questions and MCQs

Question 1141: Which of the following statements about tuberculosis (TB) of the uterus is NOT true?

A. Increase incidence of ectopic pregnancy
B. Involvement of endosalpinx
C. Most common is ascending infection (Correct Answer)
D. Mostly secondary

Explanation: ***Most common is ascending infection*** - Uterine tuberculosis is overwhelmingly due to **hematogenous spread** from a primary site, often the lungs, rather than an ascending infection from the lower genital tract. - Tuberculosis typically reaches the female genital tract by the **bloodstream**, with the fallopian tubes being the most common initial site of involvement. *Mostly secondary* - Genital tuberculosis, including uterine involvement, is almost always a **secondary infection**, meaning it results from the spread of Mycobacterium tuberculosis from another primary site in the body, most commonly the lungs. - The initial infection establishes elsewhere, and then the bacteria **disseminate hematogenously** to the reproductive organs. *Increase incidence of ectopic pregnancy* - Tubal damage and scarring caused by tuberculosis, particularly in the fallopian tubes (**salpingitis**), disrupt the normal passage of the ovum. - This anatomical alteration significantly **increases the risk** of the fertilized egg implanting outside the uterus, leading to ectopic pregnancy. *Involvement of endosalpinx* - The **fallopian tubes (endosalpinx)** are the most common site of genital tuberculosis, with eventual spread to the uterus through the lymphatic system or direct extension. - Tubal involvement can lead to **salpingitis isthmica nodosa** and hydrosalpinx, contributing to infertility and ectopic pregnancy.

Question 1142: What is the most common cause of hydrops fetalis in current medical practice?

A. Fetal infections (e.g., parvovirus B19)
B. Chromosomal abnormalities
C. Cardiac malformations (Correct Answer)
D. Rh incompatibility (historically significant)

Explanation: ***Cardiac malformations*** - **Cardiovascular abnormalities** are the **most common cause** of **non-immune hydrops fetalis** in current medical practice, accounting for **20-40%** of cases - Includes **structural heart defects** (septal defects, valvular abnormalities) and **arrhythmias** (supraventricular tachycardia, complete heart block) - These conditions lead to **heart failure** and **increased hydrostatic pressure**, causing fluid accumulation in fetal tissues and body cavities - With the near-elimination of Rh disease through immunoprophylaxis, cardiac causes have emerged as the leading etiology *Chromosomal abnormalities* - Account for **10-20%** of non-immune hydrops cases - **Turner syndrome (45,X)** is the most common chromosomal cause, associated with **cystic hygroma** and **lymphatic dysgenesis** - Other chromosomal conditions include **trisomy 21, 18, and 13**, which can cause hydrops through associated cardiac defects or other mechanisms - While significant, chromosomal causes are less common than cardiovascular causes overall *Fetal infections (e.g., parvovirus B19)* - Infections account for **5-10%** of non-immune hydrops cases - **Parvovirus B19** is the most common infectious cause, leading to severe **fetal anemia** through bone marrow suppression - Other infectious agents include **CMV**, **toxoplasmosis**, and **syphilis** - The TORCH screening helps identify treatable infectious causes *Rh incompatibility (historically significant)* - Historically the **leading cause** before the 1970s, accounting for most hydrops cases - Now accounts for **<10%** of cases due to routine **Rho(D) immune globulin (RhoGAM)** administration at 28 weeks and postpartum - Causes **immune hydrops** through maternal antibodies crossing the placenta and destroying fetal red blood cells, leading to severe anemia and heart failure - Still important in under-immunized populations or cases of missed prophylaxis

Orthopaedics

3 questions

Q1141

Osteonecrosis is seen in all except

Q1142

In neglected cases of CTEV, which joints are fused?

Q1143

What is the primary pathology associated with Congenital Dislocation of the Hip (CDH)?

NEET-PG 2012 - Orthopaedics NEET-PG Practice Questions and MCQs

Question 1141: Osteonecrosis is seen in all except

A. Fracture neck femur
B. Paget's disease (Correct Answer)
C. Perthe's disease
D. Sickle cell anemia

Explanation: ***Paget's disease*** - **Paget's disease of bone (osteitis deformans)** is a localized disorder of bone remodeling, characterized by excessive and disorganized bone formation, leading to enlarged, softened, and misshapen bones, but not directly causing osteonecrosis. - While complications like **pathological fractures** and **osteosarcoma** can occur, primary osteonecrosis is not a typical feature of Paget's disease itself. *Fracture neck femur* - **Fractures of the femoral neck** can disrupt the blood supply to the femoral head, particularly the medial circumflex femoral artery, leading to **avascular necrosis** (osteonecrosis) of the femoral head. - This is a well-known and common complication, especially in displaced fractures. *Sickle cell anemia* - **Sickle cell anemia** causes sickling of red blood cells, leading to **vaso-occlusion** and impaired blood flow to bones, resulting in **bone infarcts** (osteonecrosis). - This can affect various bones, including the femoral head, humeral head, and vertebrae. *Perthe's disease* - **Perthe's disease** (Legg-Calvé-Perthes disease) is a childhood condition characterized by **idiopathic osteonecrosis** of the femoral head. - It involves the collapse and subsequent re-ossification of the femoral epiphysis due to an interruption of its blood supply.

Question 1142: In neglected cases of CTEV, which joints are fused?

A. Calcaneocuboid, talonavicular, and talocalcaneal joints (Correct Answer)
B. Tibiotalar, calcaneocuboid, and talonavicular joints
C. None of the above joints
D. Ankle joint, calcaneocuboid, and talonavicular joints

Explanation: ***Calcaneocuboid, talonavicular, and talocalcaneal joints*** - In neglected cases of **clubfoot (CTEV)**, a **triple arthrodesis** is performed to correct the deformity. - This procedure involves the fusion of the **subtalar (talocalcaneal)**, **talonavicular**, and **calcaneocuboid joints** to provide a stable, plantigrade foot. *Tibiotalar, calcaneocuboid, and talonavicular joints* - The **tibiotalar joint (ankle joint)** is generally preserved in triple arthrodesis for CTEV to maintain ankle motion. - Fusing the tibiotalar joint would significantly **reduce ankle dorsiflexion and plantarflexion**, leading to a stiff ankle. *None of the above joints* - This option is incorrect because the fusion of specific joints is a recognized surgical treatment for severe, neglected CTEV. - **Triple arthrodesis** is a well-established procedure for correcting rigid foot deformities. *Ankle joint, calcaneocuboid, and talonavicular joints* - As mentioned, fusion of the **ankle joint (tibiotalar joint)** is generally avoided in triple arthrodesis for CTEV to preserve functional ankle motion. - The goal is to stabilize the foot while retaining as much articulation as possible in the ankle itself.

Question 1143: What is the primary pathology associated with Congenital Dislocation of the Hip (CDH)?

A. Large head of femur
B. Shallow acetabulum (Correct Answer)
C. Excessive retroversion
D. Coxa vara deformity

Explanation: ***Shallow acetabulum*** - A **shallow or dysplastic acetabulum** is the primary pathological feature in CDH, leading to an unstable or dislocated femoral head. - This anatomical abnormality prevents the femoral head from seating properly, causing **instability** and potential **dislocation**. *Large head of femur* - While femoral head abnormalities can occur, a **disproportionately large femoral head** is not the primary or most common pathological feature causing CDH. - The issue primarily lies with the **acetabular socket** rather than the size of the femoral head itself. *Excessive retroversion* - **Femoral retroversion** (backward twisting of the femoral neck relative to the femoral condyles) can be a contributing factor or an associated finding, but it is not the primary anatomical defect. - The principal pathology is the **inadequate containment** of the femoral head by a poorly formed acetabulum. *Coxa vara deformity* - **Coxa vara** is a deformity where the angle between the head and shaft of the femur is decreased. - While it can be associated with or contribute to hip instability in some conditions, it is not the primary or defining pathological feature of CDH.

Pharmacology

1 questions

Q1141

Drug of choice for Pneumocystis jirovecii in pregnancy?

Surgery

1 questions

Q1141

Volkmann's contracture: which artery is involved in this condition?