Antivirals US Medical PG Flashcards - Medical Study Cards
Master Antivirals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antivirals Flashcard Deck - 10 Cards
Flashcard 61: A major side effect of ribavirin is that it may cause _____
Answer: dose-dependent hemolytic anemia (10-20% of patients)
Extra:
Sketchy Pharmacology: GI (Hepatitis)
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 62: NNRTIs can cause _____ failure, with resulting _____ cutaneously
Answer: liver
Extra:
Watch NNRTIs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-nnrtis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 63: Live attenuated vaccines are often contraindicated in _____ and immunodeficiency
Answer: pregnancy
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/vaccinations?index=4]
https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki
Flashcard 64: Do **acyclovir, valacyclovir, or famciclovir** have activity against CMV?
_____
Answer: No
Flashcard 65: Which type of HAART drug is Dolutegravir?
_____
Answer: Integrase inhibitor
Extra:
Watch Maraviroc, fusion inhibitors, integrase inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-maraviroc-fusion-inhibitors-integrase-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 66: Do Foscarnet and Cidofovir require **viral** kinase activation?
_____
Answer: No
Extra: Unlike acyclovir and ganciclovir, foscarnet and cidofovir do not require activation by viral kinases (e.g., thymidine kinase).
- **Foscarnet**: Pyrophosphate analog (no activation required).
- **Cidofovir**: Nucleotide analog (requires host cell kinases).
Flashcard 67: HIV protease inhibitors _____ cytochrome P-450
Answer: inhibit
Extra:
Watch Protease inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-protease-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 68: NNRTIs are associated with _____, that can manifest as a more severe pathology such as Stevens-Johnson syndrome
Answer: rash
Extra:
Watch NNRTIs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-nnrtis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Toxic epidermal necrolysis/Stevens-Johnson syndrome
This 6-month-old patient presents with toxic epidermal necrolysis, the severe form of Stevens-Johnson syndrome.
Smallpox vaccination can trigger toxic epidermal necrolysis.
Stevens-Johnson syndrome following sulfonamide treatment
Blistering of skin and epidermal detachment involving the conjunctiva are visible, resembling a superficial burn.
Flashcard 69: Which NRTI may cause hyperpigmentation of palms and soles?
_____
Answer: Emtricitabine
Extra:
Watch NRTIs [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-nrtis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 70: Does Hepatitis A have a vaccine?
_____
Answer: Yes!
Extra:
Watch Hepatitis A virus (PicoRNAviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-positive-sense-hepatitis-a-virus-picornaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/vaccinations?index=6]
https://onlinemeded.org/spa/gastroenterology/viral-hepatitis/acquire?ref=anki
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